Study aims to understand how female fertility is established

Fertility is finite for mammalian females. From birth, females possess a limited number of primordial follicles, collectively called the ovarian reserve. Within each follicle is an oocyte that eventually becomes an egg. But with age, the follicles in the ovarian reserve decrease.

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Maezawa , Iwate , Japan , California , United States , Yokohama , Kanagawa , Spain , Cincinnati , Ohio , Madrid , Satoshi Namekawa , Neil Hunter , Akihiko Sakashita , Haruhiko Koseki , Margarita Salas , Yasuhisa Manukata , Chan Yeh , Emily Henderson , Hironori Abe , Richard Schultz , Miguel Vidal , University Of California , Nature Communications , Department Of Microbiology , Cincinnati Children Hospital Medical Center , Molecular Genetics , Professors Richard Schultz , Polycomb Repressive Complex , Yu Han Yeh , Cincinnati Children , Hospital Medical Center , Centro De Investigaciones Biol , Fertility , Gene , Enetics , Icrobiology , Research ,