The 8 Best San Diego Airbnbs to Rent AFAR 3/3/2021 Courtesy of Airbnb In San Diego’s buzzy, restaurant-packed Little Italy neighborhood, this top-floor escape, "Urban Retreat for Foodies in Little Italy" pairs industrial chic accents with signature West Coast flair.Sure, on its surface San Diego seems like one big beachy getaway, but zoom in further and this SoCal city is more accurately a collection of distinct neighborhoods, each with its own vibe, architecture, and food scene. There are cool-kid boutiques and craftsman homes in North Park, buzzing restaurants in bustling Little Italy, and Chicano art galleries lined up alongside traditional taquerias in Barrio Logan—and that’s in addition to the Pacific-fronting beaches and aquatic adventures that await in coastal enclaves like La Jolla and Carlsbad.