when considering another treatment, ask about xeljanz xr, a once-daily pill for adults with moderate to severe rheumatoid arthritis or active psoriatic arthritis for whom methotrexate did not work well enough. it can reduce pain, swelling, and significantly improve physical function. xeljanz can lower your ability to fight infections like tb; don't start xeljanz if you have an infection. taking a higher than recommended dose of xeljanz for ra can increase risk of death. serious, sometimes fatal infections, cancers including lymphoma, and blood clots have happened. as have tears in the stomach or intestines, serious allergic reactions, and changes in lab results. tell your doctor if you've been somewhere fungal infections are common, or if you've had tb, hepatitis b or c, or are prone to infections. don't let another morning go by without asking your doctor about xeljanz xr. ♪ skip to the good part with alka-seltzer plus. without asking your doctor about xeljanz xr.