other than there are over 50 mutations and 30 on the spike protein that the virus attaches to human cells. the nature from what we have seen can do a couple of things. one is increasing transmissability. if you have it, you are likely to pass it on to somebody else. there is concern the way the few mutations look, it is similar to others. there is a concern that none of the other mutations, beta and lambda have taken over is delta is king of the hill. if you all of a sudden are seeing variant that has mutations that may both cause greater transmissability, but also decrease efficacy of the current treatment, it might out-compete delta because cases are starting to go up in south africa.