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Lack of Mutations Associated With Favorable Prognosis in MPN-U

While the Dynamic International Prognostic Scoring System and bone marrow blasts may predict overall survival, the lack of certain mutations is also associated with a better prognosis for myeloproliferative neoplasm, unclassifiable (MPN-U).

United-states , American , Bone-marrow-pathology-group , Dynamic-international-prognostic-scoring-system , American-journal , Managed-care , Myeloproliferative-neoplasms , Mutations ,

Newsday

but we are still figuring out how to use that knowledge. should we screen all human embryos for genetic abnormalities? should we root out mutations? could we be sleepwalking into a new era of eugenics? my guest is the ethicist, disability rights activist and writer tom shakespeare, who also happens to live with a genetic condition, achondroplasia, which has restricted his growth. should we embrace difference rather than use science to root it out? tom shakespeare, welcome to hardtalk. thank you, it's great to be here. it's great to have you. now, in your personal life and your professional life,

Ethicist , Guest , Knowledge , Genetic-abnormalities , Human-embryos , Mutations , Eugenics , Era , Disability-rights-activist , Tom-shakespeare , Difference , Growth

HARDtalk

but we are still figuring out how to use that knowledge. should we screen all human embryos for genetic abnormalities? should we root out mutations? could we be sleepwalking into a new era of eugenics? my guest is the ethicist, disability rights activist and writer tom shakespeare, who also happens to live with a genetic condition, achondroplasia, which has restricted his growth. should we embrace difference rather than use science to root it out? tom shakespeare, welcome to hardtalk. thank you, it's great to be here. it's great to have you. now, in your personal life and your professional life,

Ethicist , Guest , Knowledge , Mutations , Human-embryos , Disability-rights-activist , Eugenics , Genetic-abnormalities , Era , Achondroplasia , Difference , Condition

Business News: South African rand takes a hit on fears of new Covid variant with many mutations

South African rand takes a hit on fears of new Covid variant with many mutations : Rashtra News South African rand.RapidEye | iStock | Getty ImagesThe South African rand on Friday fell sharply against the dollar after a new variant with many mutations was detected in the country.The currency fell to as low as 16.2391

South-africa , United-kingdom , Japan , United-states , Japanese , America , South-african , Adarsh-sinha , Maria-van-kerkhove , World-health-organization , Health-organization , African

Role of Small-Molecule Myosin Inhibitors in oHCM Treatment

James L. Januzzi, MD, provides insight on the pathophysiology of obstructive hypertrophic cardiomyopathy (oHCM) and comments on small-molecule myosin inhibitors as an emerging therapeutic option.

Jamesl-januzzi , Small-molecule-myosin-inhibitors , Ohcm , Treatment , Obstructive-hypertrophic-cardiomyopathy , Sarcomere , Mutations , Myocardial-hypercontractility , Lvot-obstruction ,

Expert Perspectives on Cardiac Baseline and Surveillance Testing in Immunotherapy Recipients

Javid Moslehi, MD provides expert insights into baseline and surveillance cardiac testing for individuals receiving immunotherapy.

Javid-moslehi , Afreen-shariff , Nikhil-khushalani , Onclive-insights , Melanoma , Adjuvant-melanoma , Biomarkers , Biomarker-testing , Braf , Nras , Nf1

Forward Outlook and Clinical Insights in Melanoma Treatment

A group of oncology experts provide forward-looking perspectives and clinical insights in the treatment of melanoma.

Nikhil-khushalani , Afreen-shariff , Javid-moslehi , Onclive-insights , Melanoma , Adjuvant-melanoma , Biomarkers , Biomarker-testing , Braf , Nras , Nf1

Immunotherapy-Induced Adrenal Insufficiency in Melanoma: Surveillance and Management

Afreen Shariff, MD, MBBS, examines the surveillance and management of immunotherapy-induced adrenal insufficiency in the context of melanoma, underscoring the importance of maintaining a heightened awareness for early detection.

Afreen-shariff , Javid-moslehi , Nikhil-khushalani , Melanoma , Adjuvant-melanoma , Biomarkers , Biomarker-testing , Braf , Nras , Nf1 , Mutations

Case 1: 55-Year-Old Male with Stage IIIB Melanoma Developing Immunotherapy-Induced Diabetes

Afreen Shariff, MD introduces case 1 involving a 55-year-old male with Stage IIIB melanoma who develops immunotherapy-induced diabetes.

Afreen-shariff , Treatment-approach , Evolving-treatment-strategies , Metastatic-melanoma , Year-old-male , Melanoma , Adjuvant-melanoma , Biomarkers , Biomarker-testing , Braf , Nras

Balancing Quality of Life: Adjuvant Therapy Toxicity in Melanoma Adjuvant Immunotherapy

A panel of oncology experts explores the intricate balance between maintaining quality of life and managing toxicity in adjuvant immunotherapy for melanoma.

Treatment-approach , Evolving-treatment-strategies , Metastatic-melanoma , Adjuvant-therapy-toxicity , Melanoma-adjuvant , Melanoma , Adjuvant-melanoma , Biomarkers , Biomarker-testing , Braf , Nras