Of a white house meeting with Republican Leaders today, as President Trumps handling of the virus leaves some republicans to break ranks in their responses and, of course, we have the latest on that breaking news on a new vaccine coming out of europe well tell you about that in a moment first, lets get to nbce at th haake on capitol hill for us carol, we have all these new signs, things are heading in the wrong direction, statistically, numerically in almost every state. But President Trump as we saw over the weekend still seems to be downplaying what is happening. Reporter yeah, thats right, ayman. The president continues to be on defense when it comes to his handling of the coronavirus pandemic he continues to say that things are better than they are, in terms of what were seeing in states across the country. And he was asked about this multiple times in his interview on Fox News Sunday and repeatedly every time he was ask, really found different ways to downplay the spike in cases that we have been seeing lets take a listen to what he had to say im glad we did what were doing. But we have more tests by far than any country in the world. But, sir, testing is up 37 thats good. I understand. Cases are up 194 . It isnt just the testing has gone up, it is that the virus has spread the Positivity Rate has increased many of those cases are young people that would heal in a day. They have the sniffles and we put it down as a test. It is going to disappear ill say it again. It is going to disappear and ill be right. Reporter there you have it, ill be right eventually in terms of the virus disappearing. Thats where the president is right now on coronavirus and where hes been since the beginning of the pandemic t comes against the backdrop of these negotiations that are looking like theyre going to be a lot tougher than previous negotiations with congress over another Economic Relief package and there is a lot of pressure to come up with something. And particularly this time on the president , given there are signs that the voters trust in his handling of the economy, largely stable throughout this, might be wavering. Lets dig into the possible relief bill, were approaching the end of the month, eviction notices, people say there may be a tsunami of if it if there isnt some kind of relief bill making its way through congress. Walk us through what is happening there, what are the biggest sticking points and is there anything both parties consider as must have haves . Reporter this negotiation starts off with both parties much further apart than they have been in previous negotiations we know what House Democrats want they passed a bill back in may the heroes act, outlining a 3 trillion plan for relief that includes things like extending those plussed up unemployment benefits, thats something that democrats would very much like to see be in a final bill that gets to the president s desk what were waiting on is word from republican senators, the senatecontrolled by republicans, they have yet to produce a bill of their own. We know one is being written by the Majority Leaders Office in senator mcconnells office we know that will be a topic of discussion and that white house meeting today. And we know the republicans want some things that democrats are less than entirely thrilled about including wide spectrum Liability Protection for corporations, for schools, for folks going back to work, who might then get sick with the coronavirus. And we know that they do not want to see the extension of that extra 600 a month in plussed up unemployment benefits, a number of republicans said at the time that those would disincentivize people from coming back to work. Those are two of the issues on which these sides are very far apart and the clock is ticking as you said, to get this done. All right, carol lee, garrett haake, thank you for starting us off this hour. And now some pretty significant breaking news, just this hour regarding a vaccine trial that researchers say is on pace to be ready before the end of the year just a few minutes ago, Oxford University released the results of its phase one trial that found the vaccine does create double immunity antibody cells and kills tcells. Lets translate that for you they are ready to move forward with more aggressive testing, including Clinical Trials right here in the United States. And nbc News Senior International correspondent keir simmons is in london with more on the results so give it to us in laymans terms. A lot of people may not necessarily understand the science, but how significant are the trial results here reporter it is early stage trials, but they are significant without a doubt. Just referencing what you just mentioned, im told by the researchers at Oxford University theyre preparing for a trial of 30,000 people there in the u. S. , that they think will start in just a few weeks so there is more testing to go, but what they have found and this is published in the lancet in the past hour, is that it does produce an immune response and that it is safe according to this early trial of around just over 1,000 people, and you mentioned it, one of the important aspects of this is that it appears to give you a double defense, so it acts at the antibody level and at the cellular level, so it allows the body to attack the virus when it is inside human cells, and also to attach itself to the virus to prevent it getting intocells thats laymans language just spoke to the lead researcher and he explained it a little more. Take a listen. Were getting both sides of the immune system stimulated and that is fairly unusual for vaccines we do get good antibody responses that are functionable, and neutralize the virus, they stop it infecting cells. In addition, were getting this cellular immune response with lymphocytes that can kill infected cells thats an advantage, we think that will increase the chances that this type of vaccine will be effective. Reporter just reading a little more from the news release that has just been published. It says the immune responses may be even greater after a second dose according to a subgroup of ten participants the overall test just over a thousand people and it talked about minor side effects that can be reduced by taking it. Keir simmons live in london i want to bring in ashish jha into this conversation, the director of the Harvard GlobalHealth Institute dr. Jha, always a pleasure to have you on. On days like this, when were trying to make sense of what is the Science Behind this, the Oxford University phase one trial seemingly significant, are you as optimistic as researchers there are and does this mean that we could possibly see a vaccine ready to go this year . Certainly, ayman, thank you for having me on this is good news, unequivocally this is good news for two reasons. One is as the researchers pointed out pretty much everybody got an immune response from this vaccine. And then there are two arms of your immune system, we think of humoral antibodies and t cells im pleasantly surprised by this vaccine does seem to stimulate both and that gives us that much more hope that were going to have a vaccine that will be really effective against this virus. The timeline, im not as optimistic well have it sometime this fall as i know some of the folks brought up im looking at early 2021. I would love to be wrong about that. How does Something Like this get scaled into production when youre looking at a world map that has infections in every corner on this earth and you have this company that is this university, excuse me, and we have other Companies Like moderna and other as are workin on their own trials. How does Something Like this go from a university to being scaled to meet the demands around the world right, so thats part of the challenge for why people who sort of hoped that we could have a vaccine this fall, i think are maybe being unrealistic. We have got to produce hundreds of millions, probably billions of doses of these vaccines and, you know, this is an adenovirus, you have to take a virus and modify it to get the right protein expressed. All doable, we have the technology, but to make billions of doses in a way that is safe and consistent, it is a lot of work and there are a lot of places that could fall apart. So i think, again, great news, but i dont think we want to jump the gun here. Plus, it hasnt yet really shown that it prevents infection, what it has done is shown us it has generated an immune response thats what the next phase of the Clinical Trial has to do for us is show us that. I may be thinking a few steps down the road here, but watching how the mask debate has been politicized in this country. I can only imagine what will happen when vaccines are being rolled out and you have people say take the vaccines, dont take the vaccines. How do you assure the public in this current climate that a vaccine that has some shortterm positivity in fighting the coronavirus may not have longterm side effects how do you even measure whether or not Something Like this could have a side effect five, ten, 15 years down the line . Yes, so we probably wont be able to obviously do the study for five, ten years, but from other vaccines, you dont need studies that long. Most of the negative effects will become apparent much sooner than that. But this is why we need a large scale phase three and i like the 30,000 people that they have set up in their theyre going to study in phase three and we have to follow all those people this is why, again, early fall is unrealistic, we need the time to follow people to make sure theyre not having Adverse Reactions to this vaccine. I think it is doable early 2021, im pretty optimistic were going to have or one of the other vaccines, but it is going to be hard to get it done before then. Let me switch gears for a moment and talk about how were handling the wave were in yesterday nih director Francis Collins appeared on meet the press to talk about the coun y countrys struggle to get ahead of the virus he pointed to places that did a good job that is questionable early on, but he admits that elsewhere the situation seems to have broken down listen to what he said steps were put in place and if you look to see what is happening now in those areas, they came down very close to zero but meanwhile, the rest of the country perhaps imagining this was just a new york problem kind of went about their business, didnt really pay that much attention to cdcs recommendations about the phases necessary to open up safely, and jumped over some of those hoops. Should states like florida and california, two red zone hot spots, be reverting back to a total shutdown like we saw here in new york early on well, again, im going to go off of the white houses own guidelines that were leaked out last week, theyre recommending they go back to phase one. Phase one is no gatherings greater than ten people, no bars, no indoor dining, we really do need to pull way back in these states. And if we dont do that now, by the way, universal masking, Everybody Needs to be Wearing Masks outside. If we dont do those things, were a step away from total shutdown which we want to avoid. I dont think we can avoid in these hot spots right now many of the things that people are not taking seriously enough. Dr. Ashish jha, thank you very much, covering a lot of grounds there this morning i appreciate your time as always. The breaking news, a massive manhunt is under way after a federal judges son is dead and her husband in Critical Condition after a man dressed as a Delivery Driver opened fire at their new jersey home. The judge ester salas was reportedly in the basement of the home at the stim and was not injured in that shooting salas is an obama appointee and first hispanic federal judge from the state of new jersey she handled several high profile cases including the sentencing of two real housewives stars salas is also overseeing a lawsuit charging Deutsche Bank officials with failing to flag suspicious transactions made by jeffrey epstein. The gunman is still at large and well bring you any developments as they happen much more news ahead about the pandemic including a fact check on President Trumps claims that the u. S. Is seeing more covid cases because we have increased testing believe it or not. And were going to honor the life and legacy of civil rights icon congressman john lewis. Up next, new clashes involving protesters in portland, oregon, overnight, days after the Trump Administration ignited tensions by sending federal agents to the city, were going to talk to congresswoman Suzanne Bonamicci who says the officers with not welcome in her state and are calling for inspectors general to investigate these actions stay with us thousands of women with metastatic Breast Cancer, which is Breast Cancer that has spread to other parts of the body, are living in the moment and taking ibrance. Ibrance with an aromatase inhibitor is for postmenopausal women or for men with hr her2 metastatic Breast Cancer, as the first hormonal based therapy. Ibrance plus letrozole significantly delayed disease progression versus letrozole, and shrank tumors in over half of patients. Patients taking ibrance can develop low white blood cell counts, which may cause serious infections that can lead to death. Ibrance may cause severe inflammation of the lungs that can lead to death. Tell your doctor right away if you have new or worsening symptoms, including trouble breathing, shortness of breath, cough, or chest pain. Before taking ibrance, tell your doctor if you have fever, chills, or other signs of infection, liver or kidney problems, are pregnant, breastfeeding, or plan to become pregnant. Common side effects include low red blood cell and low platelet counts, infections, tiredness, nausea, sore mouth, abnormalities in liver blood tests, diarrhea, hair thinning or loss, vomiting, rash, and loss of appetite. Be in your moment. Ask your doctor about ibrance. Come on in, were open. All we do is hand you the bag. Simple. Done. We adapt and we change. You know, you just figure it out. Weve just been finding a way to keep on pushing. Overnight, clashes continue to escalate in portland, with the Trump Administration deploying federal agents to the city and protesters gathering for the 53rd straight night. The protests have been going on there since the death of george floyd two months ago but they were done they were down to just dozens of people until those federal agents arrived about a week ago now the white house is actually facing widespread backlash for the increased federal presence it has ordered there the state of oregon now suing federal agencies for allegedly violating protesters civil rights and congress is calling for new investigations into this crackdown. As for President Trump, he says hes trying to help portland, oregons governor and the citys mayor say they never asked for washingtons help, but the head of Homeland Security said this morning they dont need an invitation i dont need invitations by the state, state mayors or state governors to do our job. Were going to do that whether they like us there or not. Thats our responsibility. Nbcs Erin Mclaughlin is in portland this morning. What exactly is happening there on the ground . Reporter hey, ayman. At the moment, it is pretty calm here outside of the federal courthouse this has been the flashpoint night after night, certainly was the flashpoint last night, protesters storming this steel fencing that you see here and some places breaking it down but now as you can see the situation is under control once again. It was a real Cross Section of people out last night. We spoke to one mom, selfdescribed mom, mother of two, first time protester, she said that she saw federal agents arresting people here in portland, putting them into unmarked vehicles and it made her so upset, she felt she needed to come out and exercise her constitutional right take a listen to what Beverly Barnum had to say. Why was it important for you to be here at the federal courthouse last night . I think it just boils down to humanity, humanitarian rights being violated over and over again. And also i see a segment of our population being violence and i figure if i can get some moms out here, maybe we would quell some of the violence, people wouldnt feel the need to throw Water Bottles or throw rocks or throw bricks they would have us to protect them reporter and barnum was out last night with the socalled wall of moms they were holding daisies, one of the daisies there in the fence this morning, left behind from the nights chaos in terms of what we can expect Going Forward today, it is possible that the attorney general will be in court, we dont have exact timing on that, but she said she intends to fill a temporary restraining order against the department of Homeland Security to stop federal agents from abusing what she argues is making unlawful arrests. Meanwhile, the department of Homeland Security tweeting out that one federal agent was injured in last nights chaos, reiterating theyre here to protect federal property ayman . Erin mclaughlin for us this morning, thank you, erin, stay safe. Joining us now is congresswoman suzanne bonamici, dem