I recently wrote an April Fool piece about an imaginary drug company that invested a billion dollars in a COVID vaccine, but when they ran it through Phase 3 clinical trials it fell just short of statistical significance for effectiveness. “Shucks! Back to the drawing board.” They report the results exactly as the occurred and abandon the vaccine. The joke, of course, is that no drug company behaves in this way. From our vantage out here in consumerland, all vaccine trials are successful. Can you call it “science” if there is only one acceptable outcome of the experiment? Banks that are “too big to fail” cost the public hundreds of billions of dollars. Drugs that are “too big to fail” can cost hundreds of thousands of lives.