In the second year of the COVID-19 pandemic, widespread distribution and administration of vaccines are raising hopes of achieving herd immunity—and returning to some sense of normalcy—in the U.S. Right now, vaccine supply is below demand, but that will soon change. Health care providers, long-term care facilities, airlines, restaurants, universities, and other entities are currently considering, or have already implemented, COVID-19 vaccine mandates, leaving Americans wondering whether these entities can require them to get vaccinated. The short answer is yes, though different kinds of requirements apply in different situations. Vaccine mandates are legal (within specific parameters) as affirmed by the U.S. Supreme Court in 1905’s