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Researchers Reveal How Critical Part of Lung Forms at Cellular Level


Date Time
Researchers Reveal How Critical Part of Lung Forms at Cellular Level
Researchers from Children’s Hospital of Philadelphia (CHOP) have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air. Understanding this process gives researchers a better sense of how to develop therapies and potentially regenerate this critical tissue in the event of injury. The findings were published online today by the journal Science.
The lung develops during both embryonic and postnatal stages, during which lung tissue forms and a variety of cell types perform specific roles. During the transition from embryo to newborn is when the alveolar region of the lung refines its primary function of exchanging gas, which includes the critical process of ridding the body of carbon dioxide. ....

University Of Pennsylvania , United States , Jaroda Zepp , Division Of Pulmonary , National Institutes Of Health , Perelman School Of Medicine , Sleep Medicine , Assistant Professor , Perelman School , National Institutes , Children 039s Hospital Of Philadelphia , Cell Development , Carbon Dioxide , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா , ஒன்றுபட்டது மாநிலங்களில் , ஜரோடா ஜேப்ப் , பிரிவு ஆஃப் நுரையீரல் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , பெரல்மேன் பள்ளி ஆஃப் மருந்து , தூங்கு மருந்து , உதவியாளர் ப்ரொஃபெஸர் , பெரல்மேன் பள்ளி , தேசிய நிறுவனங்கள் , செல் வளர்ச்சி ,

Lifetime of mathematical achievement recognised


Professor Mathai Varghese FAA
The University of Adelaide’s Professor Mathai Varghese FAA has been awarded the prestigious Hannan Medal by the Australian Academy of Science for his career-long outstanding contributions in the field of geometric analysis.
Professor Varghese is Elder Professor of Mathematics and Australian Laureate Fellow in the School of Mathematical Sciences. Since 2009, he has been Director of the Institute for Geometry and its Applications at Adelaide. Since joining the University of Adelaide in 1989 he has held various ARC Postdoctoral positions and was appointed Professor of Pure Mathematics in 2006 and the Elder Chair in Mathematics in 2013. He completed his PhD at the Massachusetts Institute of Technology in 1986 and was a postdoctoral researcher (Dickson Instructor) at the University of Chicago. ....

University Of Adelaide , South Australia , Institute For Geometry , Massachusetts Institute Of Technology , Australian Mathematical Society , School Of Mathematical Sciences , University Of Chicago , Australian Academy Of Science , University Of Adelaide Professor Mathai Varghese , Professor Mathai Varghese , Hannan Medal , Australian Academy , Elder Professor , Australian Laureate Fellow , Pure Mathematics , Elder Chair , Massachusetts Institute , Dickson Instructor , Large Grants , Discovery Projects , Professor Varghese , Australian Laureate Fellowship , தெற்கு ஆஸ்திரேலியா , நிறுவனம் க்கு வடிவியல் , மாசசூசெட்ஸ் நிறுவனம் ஆஃப் தொழில்நுட்பம் , ஆஸ்திரேலிய கணித சமூகம் ,

A simple step to enhance CRISPR-Cas9 genome editing


Kyoto University
The Hotta lab shows that protection from cellular RNA enhances the genome editing of iPS cells.
The ability for scientists to edit human genomic DNA has been around for decades. Such research has revealed how a single mutation in just one of the billions of base pairs in the human genome can cause destructive diseases. In the past decade, advances in CRISPR-Cas9 technology have taken DNA editing a major step farther and promise to revolutionize regenerative medicine. One of the biggest challenges for therapeutic application is the efficiency of precise genome editing. A new study by Junior Associate Professor Akitsu Hotta and colleagues reports a simple but key step in the delivery of CRISPR-Cas9 into iPS cells that enhances this efficiency. ....

Takahiro Iguchi , Peter Gee , Miyuki Ono , Akitsu Hotta , Yuto Kita , Huaigeng Xu , Xiouh Wang , Noriko Sasakawa , Akihiro Kagita , Ps Cell Research , Department Of Clinical Application , Cira Foundation , Kyoto University , Junior Associate Professor Akitsu Hotta , Mandy Lung , Stem Cell , Clinical Application , Regenerative Medicine , பீட்டர் ஜீ , மியூகி ஓனோ , ப்ச் செல் ஆராய்ச்சி , துறை ஆஃப் மருத்துவ விண்ணப்பம் , சிரா அடித்தளம் , கியோட்டோ பல்கலைக்கழகம் , மண்டி நுரையீரல் , தண்டு செல் ,