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KARACHI: The Aga Khan University has received $1.5 million grant from Wellcome Leap to transform treatment of -Thalassemia and Sickle Cell Disease , which have plagued South Asia, particularly...
July 1, 2021 Innovative gene-editing therapies for two significant blood disorders, beta thalassemia and sickle cell anaemia, have received a boost with the AKU’s Centre for Regenerative Medicine and Stem Cell Research, CRM, winning a competitive research grant of Rs159.60 million ($1.02 m) to look for a genetic ‘fix’. Thalassemia and sickle cell disease are genetic disorders, passed down from parent to child, and are common in Pakistan. There are as many as 100,000 transfusion-dependent thalassemia patients in the country. Every year another 5,000 babies are born with the disorder. On...
KARACHI: Efforts to find less-invasive and more affordable cure for two common genetic disorders — beta thalassaemia and sickle cell anaemia — have received a boost with Aga Khan University’s research centre recently winning a competitive research grant of Rs159.60 million. Currently, Pakistan has an estimated 100,000 transfusion-dependent thalassaemia patients with 5,000 babies born with the disease every year. On the other hand, sickle-cell disease is one of the well-known causes of anaemia in the country. Doctors and research scientists are aware that mutations in the haemoglobin bet...
Karachi January 21, 2021 The Aga Khan Universityâs Centre for Regenerative Medicine and Stem Cell Research (CRM) has won a Rs14.5 million grant to develop new, targeted therapies for a common form of blood cancer in adults, Philadelphia chromosome positive (Ph+) leukaemia. The chromosomal defect known as Philadelphia chromosome (Ph) is a characteristic of two important types of blood cancer: chronic myeloid leukaemia (CML) and Ph positive acute lymphoblastic leukaemia (Ph+ ALL). The Ph chromosome is formed when chromosome 9 and 22 break and exchange portions which leads to creation of a...