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Lung Disease Raises Risk Of Heart Conditions Regardless Of Other Factors: Study

The researchers made the interesting finding using a trial involving patients with a rare genetic condition called Alpha-1 antitrypsin deficiency (AATD). ....

Robert Stockley , Louise Crowley , University Of Birmingham , Orphanet Journal , Healthy Living , Lung Disease , Cardiovascular Disease Risk , Heart Condition , Rsik Factors , Alpha 1 Antitrypsin Deficiency ,

Inhibrx, Sanofi ratify $2.2B deal for AATD therapy

Inhibrx Inc. and Sanofi SA have agreed to a deal worth up to $2.2 billion, whereby the latter’s Aventis Inc. subsidiary will acquire INBRX-101, an optimized, recombinant alpha-1 antitrypsin (AAT) augmentation therapy undergoing a registrational trial for AAT deficiency (AATD), an inherited genetic disorder caused by single nucleotide variants in the SERPINA1 gene. ....

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Takeda Canada Inks Contract With Canadian Blood Services For GLASSIA

Takeda Canada Inc., the Canadian arm of Japan's Takeda Pharmaceutical Co. Ltd. (TAK) on Wednesday entered into a contract with Canadian Blood Services (CBS) for GLASSIA (alpha-1 proteinase inhibitor) resulting from CBS's request for proposal for hereditary deficiency of Alpha-1 Antitrypsin Deficiency (Alpha-1). ....

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Augmentation therapy can save lives of people with alpha-1 antitrypsin deficiency, study shows

Boosting levels of a deficient protein has clear survival benefits for people with the genetic condition alpha-1 antitrypsin deficiency (AATD), according to new research led by RCSI University of Medicine and Health Sciences. ....

United States , Daniel Fraughen , Gerry Mcelvaney , Geraldine Kelly , Lily Ramsey , Irish Centre For Genetic Lung Disease , Health Sciences , University Of Medicine , Foundation Ireland , Department Of Medicine , American Journal , Critical Care Medicine , Irish Centre , Genetic Lung Disease , Senior Lecturer , Chief Scientist , Professor Gerry Mcelvaney , Alpha 1 Antitrypsin Deficiency , Critical Care , Liver Disease , Ung Disease ,