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Quarterly, Semiannual Zilebesiran Injection Improves Blood Pressure Control

Zilebesiran targets hepatic angiotensinogen production. Investigators evaluated the blood pressure-lowering ability and safety of various zilebesiran dosing regimens. ....

United States , University Of Chicago , Georgel Bakris , Mortimerb Davis , Ernestol Schiffrin , University Of Chicago Medicine , American Heart Association Comprehensive Hypertension Center , Lady Davis Institute Of Medical Research , Chicago Medicine , Lady Davis Institute , Medical Research , Sir Mortimer , Jewish General Hospital ,

RNA Interference With Zilebesiran for Mild to Moderate Hypertension

This phase 2 randomized trial examines the antihypertensive efficacy and safety of different zilebesiran dosing regimens. ....

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Hypertension: Novel drug helped lower blood pressure for 6 month

A single dose of an experimental medication called zilebesiran was safe and effective in lowering blood pressure for 6 month, a study finds. ....

United States , United Kingdom , Nilesh Samani , Jennifer Wong , Georgel Bakris , Han Chen , Vascular Institute At Orange Coast Medical Center , Miami Cardiac Vascular Institute , University Of Chicago Medicine , Baptist Health South Florida , American Heart Association Comprehensive Hypertension Center , British Heart Foundation , Chicago Medicine , Medical News , Cheng Han Chen , Structural Heart Program , Memorialcare Saddleback Medical Center , Laguna Hills , Non Invasive Cardiology , Memorialcare Heart , Vascular Institute , Orange Coast Medical Center , Fountain Valley , Ian Del Conde , Miami Cardiac , Del Conde ,

Injectable antihypertensive drug lowers blood pressure for up to 6 months

Injectable antihypertensive drug lowers blood pressure for up to 6 months
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United States , Georgel Bakris , American Heart Association Comprehensive Hypertension Center , University Of Chicago Medicine , Cardiology Today Editorial Board Member George , Chicago Medicine ,

Alnylam Presents Positive Results from the KARDIA-1 Phase 2 Dose-Ranging Study of Zilebesiran, an Investigational RNAi Therapeutic in Development for the Treatment of Hypertension in Patients at High Cardiovascular Risk

– Zilebesiran Met Primary Endpoint Demonstrating Up to 16.7 mmHg Placebo-Adjusted Reduction of 24-Hour Mean Systolic Blood Pressure at Three Months of Treatment –

– Study Met Key Secondary. ....

United States , United Kingdom , Georgel Bakris , Simon Fox , University Of Chicago Medicine , Alnylam Pharmaceuticals Nasdaq , Alnylam Pharmaceuticals , Alnylam Pharmaceuticals Inc , Zilebesiran Program Lead At Alnylam , Health Promotion Series , American Heart Association Scientific Sessions , World Health Organization , American Heart Association Comprehensive Hypertension Center , Securities Exchange , Exchange Commission , American Heart Association , Journal Of The American College Cardiology , Scientific Sessions , Professor George , Board Certified Hypertension Specialist , Hour Mean Ambulatory , Vice President , Zilebesiran Program Lead , Renin Angiotensin Aldosterone System , Enhanced Stabilization Chemistry Plus , Nobel Prize Winning ,