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Seagate developing dual-layer, heat-assisted magnetic recording tech for 120TB HDDs

Seagate recently introduced its Mozaic 3+ storage platform, which implements HAMR technology for 30TB hard disk drives. The US storage giant is now collaborating with Sony to...

Acta-materialia , Sony , Tohoku-university , Perpendicular-magnetic-recording , Shingled-magnetic-recording , Heat-assisted-magnetic-recording , Seagate , Torage , Amr ,

"The faecal microbiome of the Australian silver gull contains phylogene" by Ethan R. Wyrsch, Bethany J. Hoye et al.

Wildlife are implicated in the dissemination of antimicrobial resistance, but their roles as hosts for Escherichia coli that pose a threat to human and animal health is limited. Gulls (family Laridae) in particular, are known to carry diverse lineages of multiple-antibiotic resistant E. coli, including extra-intestinal pathogenic E. coli (ExPEC). Whole genome sequencing of 431 E. coli isolates from 69 healthy Australian silver gulls (Chroicocephalus novaehollandiae) sampled during the 2019 breeding season, and without antibiotic selection, was undertaken to assess carriage in an urban wildlife population. Phylogenetic analysis and genotyping resolved 123 sequence types (STs) representing most phylogroups, and identified diverse ExPEC, including an expansive phylogroup B2 cluster comprising 103 isolates (24 %; 31 STs). Analysis of the mobilome identified: i) widespread carriage of the Yersinia High Pathogenicity Island (HPI), a key ExPEC virulence determinant; ii) broad distribution of two novel phage elements, each carrying sitABCD and iii) carriage of the transmissible locus of stress tolerance (tLST), an element linked to sanitation resistance. Of the 169 HPI carrying isolates, 49 (48 %) represented diverse B2 isolates hosting FII-64 ColV-like plasmids that lacked iutABC and sitABC operons typical of ColV plasmids, but carried the serine protease autotransporter gene, sha. Diverse E. coli also carried archetypal ColV plasmids (52 isolates; 12 %). Clusters of closely related E. coli (<50 >SNVs) from ST58, ST457 and ST746, sourced from healthy gulls, humans, and companion animals, were frequently identified. In summary, anthropogenically impacted gulls host an expansive E. coli population, including: i) putative ExPEC that carry ColV virulence gene cargo (101 isolates; 23.4 %) and HPI (169 isolates; 39 %); ii) atypical enteropathogenic E. coli (EPEC) (17 isolates; 3.9 %), and iii) E. coli that carry the tLST (20 isolates; 4.6 %). Gulls play an important role in the evolution and transmission of E. coli that impact human health.

Australia , Australian , Yersinia-high-pathogenicity-island , Amr , Acteria , Pidemiology , Scherichia-coli , Enome-sequencing , Irulence ,

Mutual Advisors LLC Lowers Holdings in Alpha Metallurgical Resources, Inc. (NYSE:AMR)

Mutual Advisors LLC trimmed its position in Alpha Metallurgical Resources, Inc. (NYSE:AMR – Free Report) by 5.1% in the 3rd quarter, according to its most recent 13F filing with the Securities and Exchange Commission. The firm owned 7,650 shares of the energy company’s stock after selling 412 shares during the quarter. Mutual Advisors LLC owned […]

Virginia , United-states , West-virginia , Lazard-asset-management , Mutual-advisors , Contura-energy-inc , Exchange-commission , Alpha-metallurgical-resources-inc , Macquarie-group-ltd , Exchange-traded-concepts , Alpha-metallurgical-resources

Alpha Metallurgical Resources, Inc. (NYSE:AMR) Shares Sold by Mutual Advisors LLC

Mutual Advisors LLC lowered its stake in Alpha Metallurgical Resources, Inc. (NYSE:AMR – Free Report) by 5.1% during the 3rd quarter, according to its most recent Form 13F filing with the SEC. The institutional investor owned 7,650 shares of the energy company’s stock after selling 412 shares during the period. Mutual Advisors LLC’s holdings in […]

West-virginia , United-states , Virginia , Alpha-metallurgical-resources-inc , Meeder-asset-management-inc , Eqis-capital-management-inc , Mutual-advisors , Sei-investments-co , Contura-energy-inc , Advisor-group-holdings-inc , Alpha-metallurgical-resources

FDA Approves Enmetazobactam for Complicated UTIs: A Breakthrough in Antimicrobial Therapy

Enmetazobactam (Exblifep; Orchid Pharma) has received FDA approval for treating complicated urinary tract infections (cUTIs), offering a promising solution in the battle against antimicrobial resistance.

United-states , Enmetazobactam-exblifep , Adobe-stock , Dancing-man , Orchid-pharma , New-drug-approval , Qualified-infectious-disease-product , New-drug-application , Urinary-tract , Amr , Cuti ,

Multnomah County debates change in ambulance response model amidst community concern

A group of Multnomah County Commissioners say they&rsquo;re worried that the community is not getting the care it deserves.CONTINUING COVERAGE | Multnomah County lays

United-states , American , Rene-gonzalez , Jessica-vega-pederson , Vega-pederson , Sharon-meieran , Jonathan-jui , Rob-mcdonald , American-medical-response , Emergency-medical-services , Multnomah-county-commissioners , Medical-response

Antibiotic Apocalypse: Scientists, startups fight antibiotic apocalypse - News Article | India News

India News: Read about how scientists and startups are working together to fight the antibiotic apocalypse. Learn about the challenges of antimicrobial resistance (AMR) and the efforts to develop new classes of antibiotics. Stay informed with the latest news on this important issue.

Boston , Massachusetts , United-states , Bengaluru , Karnataka , India , Alexander-fleming , Anand-anandkumar , Bay-area , Ndia-news , Ndia-news-today