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Welcome To IANS Live - SCIENCE-AND-TECHNOLOGY - High BP may speed up bone ageing, says study

In lab studies on rats, they found that when compared to the young mice without hypertension, the young mice with induced hypertension had a significant 24 per cent reduction in bone volume fraction.They ....

New York , United States , Vanderbilt University , Elizabeth Maria Hennen , American Heart Association Hypertension Scientific Sessions , Vanderbilt University In Nashville , American Heart Association , Hypertension Scientific Sessions ,

N501Y mutation and SARS-CoV-2 spike protein-angiotensin-converting enzyme-2 binding

In a new study, researchers assessed the effects of N501Y mutation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein on binding to angiotensin-converting enzyme-2 (ACE-2). ....

Coronavirus Disease Covid 19 , Ars Cov 2 , Spike Protein , Binding Affinity , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors. ....

Kateryna Kon Shutterstock , Research Square , World Health Organization , Middle East , Ngiotensin Converting Enzyme 2 , Coronavirus Disease Covid 19 , Ers Cov , Ars Cov 2 ,

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions. ....

United States , Kateryna Kon Shutterstock , National Center , University Of North California , Translational Sciences , North California , Advancing Translational Sciences , Multi Descriptor Read Across , Ngiotensin Converting Enzyme 2 , Ars Cov 2 , Covid 19 , High Throughput , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein. ....

Aimee Molineux , Neha Mathurmar , Neha Mathur , Kateryna Kon Shutterstock , Trends In Pharmacological Sciences , Pharmacological Sciences , Ngiotensin Converting Enzyme 2 , Coronavirus Disease Covid 19 , Covid 19 , Binding Affinity , N Vitro , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,