Antipsychotic Use in Pregnancy: New Data
New data suggest that antipsychotics are not major teratogens, providing additional reassurance for pregnant women who need these medications.
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New data suggest that antipsychotics are not major teratogens, providing additional reassurance for pregnant women who need these medications.
Researchers reported that a phase 3 study showed statistically significant improvement in patients with agitation related to Alzheimer's who took the atypical antipsychotic brexpiprazole.
Author summary Why was this study done? Compared to Alzheimer’s disease (AD), dementia with Lewy bodies (DLBs) is associated with accelerated cognitive decline, lower quality of life, higher caregiver burden, shorter lifespan, and higher costs of care, as well as increased rates of admission to general hospitals and residential care and longer length of stay. Although there are no disease-modifying medications for DLB, there is evidence suggesting that acetylcholinesterase inhibitors (AChEIs) and glutamate N-methyl-D-aspartate receptor antagonists (specifically, memantine) are efficaci...
Experts point to the harms of drug companies’ influence on research, practice, and education in healthcare.
A genetic postmortem analysis of the brains of patients with schizophrenia suggests the dysfunction of dopamine receptors in the caudate nucleus may play a role in causing cause the disorder.