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Scientists flag previously overlooked type of immune cell as suspected source of severe COVID-19

Scientists flag previously overlooked type of immune cell as suspected source of severe COVID-19
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

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Stanford Medicine study flags unexpected cells in lung as suspected source of severe COVID

Stanford Medicine study flags unexpected cells in lung as suspected source of severe COVID
stanford.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from stanford.edu Daily Mail and Mail on Sunday newspapers.

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Study reveals unexpected vulnerability of lung immune cells to SARS-CoV-2

The lung-cell type that's most susceptible to infection by SARS-CoV-2, the virus that causes COVID-19, is not the one previously assumed to be most vulnerable.

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Bay Briefing: How likely is the variant 'doomsday scenario'?

Plus: More travelers are seeking the comfort of private flying

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COVID-19 severity affected by proportion of antibodies targeting crucial viral protein

E-Mail
COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine.
The findings identify new links between the course of the disease and a patient's immune response. They also raise concerns about whether people can be re-infected, whether antibody tests to detect prior infection may underestimate the breadth of the pandemic and whether vaccinations may need to be repeated at regular intervals to maintain a protective immune response.
"This is one of the most comprehensive studies to date of the antibody immune response to SARS-CoV-2 in people across the entire spectrum of disease severity, from asymptomatic to fatal," said Scott Boyd, MD, PhD, associate professor of pathology. "We assessed multiple time points and sample types, and also analyzed levels of viral RNA in patient nasopharyngeal swabs and blood samples. It's one of the first big-picture looks at this illness."

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