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Plexin-A1 gene plays a more extensive role in brain development, study shows Study by the University of Bonn shows that mutations of the investigated gene manifest in different patterns of inheritance. The so-called Plexin-A1 gene seems to play a more extensive role in brain development than previously assumed. This is shown by a current study led by the University Hospital Bonn and the Institute of Anatomy of the University of Bonn with more than 60 international partners. The gene is also interesting for another reason: Its mutations are inherited either dominantly or recessively, depending on which part of the gene is affected. The results of the study are now published in the journal Genetics in Medicine . ....