Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses
Researchers generated six human monoclonal antibodies that prevented infection.
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Researchers generated six human monoclonal antibodies that prevented infection.
In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.
Researchers in the US examined the neutralization evasion and receptor affinity properties of SARS-CoV-2 Omicron BA.2.75 sub-variants.
In a recent study published in the journal mBio, researchers in the United States evaluated rat exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC).
In a recent study posted to the bioRxiv* preprint server, researchers engineered epitope scaffolds (ESs) of conserved regions of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein.