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Kyushu University researchers find that one of the causes of CKD induced heart failures is the over expression of G protein-coupled receptor 68 in monocytes. Monocyte disruption was caused by the activation of the Clock gene, the key regulator of circadian rhythm via the increased level of vitamin A in the body resulting from kidney dysfunction.
Scientists from the Immuno-Pharmacology and Interactomics group at the Luxembourg Institute of Health (LIH), in collaboration with the Center for Drug Discovery at RTI International (RTI), have demonstrated that conolidine, a natural painkiller derived from the pinwheel flower and traditionally used in Chinese medicine, interacts with the newly identified opioid receptor ACKR3/CXCR7 that regulates opioid peptides naturally produced in the brain. The researchers also developed a synthetic analogue of conolidine, RTI-5152-12, which displays an even greater activity on the receptor.
E-Mail IMAGE: Wilker notes that not everyone in his lab has a chemistry degree; some of the lab members are shellfish -- about 1,000 of them to be exact. The shellfish play... view more Credit: Purdue University photo/Rebecca McElhoe Don't look now, but you're surrounded. Really. Within arm's reach - probably even touching you - are troublesome, sticky, potentially even toxic, substances. Bad for the planet, permanent, maybe even bad for your health. They're in your shoes, in your phone, in your laptop, lurking in the folds of envelopes, on books, in the chair you're sitting in, the...
In a paper published in NANO, researchers from Guizhou Meiling Power Sources Co., Ltd., China have reviewed the recent progress in biopolymer-based electrolyte. The biopolymer materials with unique characteristics including water solubility, film-forming capability and adhesive property played a key role in the design of zero pollution lithium battery. The biopolymers mentioned in this review were polysaccharide, protein, natural rubber and other polymers.
This study aimed to assess the prognostic value of cTnI in COVID-19 patients.