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 E-Mail IMAGE: Starting from a liquid alpha hydroxy acid monomer library, drying through heating results in synthesis of polyester polymers, which form a gel-like state. This gel is then rehydrated, resulting in... view more  Credit: Tony Z. Jia All modern life is composed of cells, from single-celled bacteria to more complex organisms such as humans, which may contain billions or even trillions of cells, but how life came to be cellular remains uncertain. New research led by specially appointed assistant professor Tony Z. Jia at the Earth-Life Science Institute (ELSI) at Tokyo Inst...

Credit: Stefan Zimmerman New research at Karolinska Institutet in Sweden suggests a link between psychosis and a genetic change that affects the brain's immune system. The study published in Molecular Psychiatry may impact the development of modern medicines for bipolar disorder or schizophrenia. Psychosis affects approximately 2-3 per cent of the population and is characterized by a change in the perception of reality, often with elements of hallucinations and paranoid reactions. Most of the people affected are patients with schizophrenia, but people with bipolar disorder may also experien...

 E-Mail By Karina Ninni | Agência FAPESP – A study of 92 adolescents conducted in Brazil suggests girls are more likely than boys to develop metabolic alterations associated with obesity, such as high blood pressure and excessive blood levels of cholesterol and triglycerides (dyslipidemia). The study was conducted with FAPESP’s support by scientists affiliated with the University of São Paulo’s Biomedical Sciences Institute (ICB-USP) and the Medical School of Santa Casa de Misericórdia de São Paulo (FCM-SCMSP). The findings are reported in an article in the journal Frontiers in...

Credit: Angelo Frei / Imperial College London Researchers have created a probe that glows when it detects an enzyme associated with issues that can lead to blood clots and strokes. The team of researchers, from the Department of Chemistry and the National Lung and Heart Institute at Imperial College London, demonstrated that their probe quickly and accurately detects the enzyme in modified E. Coli cells. They are now expanding this proof-of-concept study, published in the Journal of the American Chemical Society and funded by the British Heart Foundation (BHF), with the hope of creating rapi...

 E-Mail In a number of biological processes, iron-sulfur clusters play a vital role, where they act as cofactors to enzymes. Research published in Angewandte Chemie now shows that cubic clusters can support unusual bonding states. This study shows that the cluster copes well with a multiple bond between iron and nitrogen--a structural motif that may be involved in biological nitrogen fixation. Clusters made of iron and sulfur atoms are essential cofactors for a number of enzymes, especially in biological processes involving electron transfer. As an example, nitrogen-fixing bacteria use iron...