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 E-Mail IMAGE: Schematic of the co-planar light-actuated optoelectrowetting microfluidic device that features an integrated metal mesh grid. A droplet on the device surface is actuated and moved around the two-dimensional plane under... view more  Credit: Jodi Loo et al. doi: 10.1117/1.JOM.1.3.034001. Microfluidic technologies have seen great advances over the past few decades in addressing applications such as biochemical analysis, pharmaceutical development, and point-of-care diagnostics. Miniaturization of biochemical operations performed on lab-on-a-chip microfluidic platforms b...

 E-Mail IMAGE: Mass spectrometer analysis of blood serum in diabetic patients. 1) SH-Albumin (unmodified), 2) Cys-Albumin (cysteine adduct (oxidized albumin), 3) Glu-Albumin (sugar adduct), 4) Cys-Glu-Albumin (simultaneous cysteine and sugar adduct), 5)... view more  Credit: Associate Professor Hiroshi Watanabe A research group from Kumamoto University, Japan has discovered that cysteinylated albumin (oxidized albumin) in serum can be used as an early diagnostic marker for diabetic kidney disease. Compared with urinary albumin, serum oxidized albumin not only reflects renal patholog...

Inserm teams led by Laurent Reber (Infinity, Toulouse) and Pierre Bruhns (Humoral Immunity, Institut Pasteur, Paris) and French company NEOVACS have developed a vaccine that could induce long-term protection against allergic asthma, reducing the severity of its symptoms and thus significantly improving patient quality of life. Their research in animals has been published in the journal Nature Communications.

An international team of researchers has analyzed the function of the histone demethylase KDM5A in multiple myeloma, one of the three major hematological cancers, and clarified the mechanism by which it promotes myeloma cell proliferation. They also developed a novel KDM5 inhibitor and showed that it inhibits cancer cell growth in a myeloma mouse model. The researchers expect that new therapies targeting KDM5A will be developed in the future.

 E-Mail IMAGE: Constantine Simintiras and his colleagues in Thomas Spencer's lab have found a non-invasive way to study fluid produced in the uterus during pregnancy. view more  Credit: University of Missouri. The quest to create safer, more successful pregnancies is one of the top goals of modern science. While pregnancy is better understood today than ever before, with improvements in technology helping to lower the risk of negative outcomes, there is much researchers still don't know about a vital part of the pregnancy process: uterine fluid. Secreted by glands in the uterus duri...