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The human Y chromosome has been notoriously difficult to sequence and assemble because of its complex repeat structure that includes long palindromes, tandem repeats and segmental duplications1–3. As a result, more than half of the Y chromosome is missing from the GRCh38 reference sequence and it remains the last human chromosome to be finished4,5. Here, the Telomere-to-Telomere (T2T) consortium presents the complete 62,460,029-base-pair sequence of a human Y chromosome from the HG002 genome (T2T-Y) that corrects multiple errors in GRCh38-Y and adds over 30 million base pairs of se...

The Nobel Prize in Physiology or Medicine 2022 was awarded to Svante Pääbo "for his discoveries concerning the genomes of extinct hominins and human evolution"

Researchers develop method to study ancient human DNA preserved by head lice.