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'Smart' Skin Patch the Future of Early Alzheimer's Diagnosis?

A new skin patch that incorporates microneedles can detect the proinflammatory cytokine IL-6 in the lab, suggesting it may have the potential to diagnose preclinical Alzheimer s and other diseases. ....

United States , United Kingdom , Sanjiv Sharma , Davidk Simon , Harvard Medical School , Polytechnic Of Porto School Engineering , Swansea University In Wales , Medscape Medical , Swansea University , Oporto School , Medscape Medical News , Alzheimers Disease , Lzheimer Disease , Iological Marker , Parkinsons Disease , Biologic Therapy , Healthcare And Medical Technology , Ealth And Medical Tech , Ealth And Med Tech , Ealth And Medical Technology , Neurodegenerative Disease , Point Of Care , Transdermal Drug , Rug Transdermal , Memory Problems , Nerve Cell ,

Improving Osteoarthritis Diagnosis Through a More Accurate Blood Test

Progression of osteoarthritis in the knee can be identified more accurately than current methods according to a new study. ....

Steoarthritis Progression , Iomarker Based Blood Test , Blood Test ,

How Should PRAME Be Used to Evaluate Melanocytic Lesions?

One potential pitfall with the test is that sun-damaged melanocytes may express PRAME, according to Cora Humberson, MD. ....

San Diego , United States , Cora Humberson , Scripps Md Anderson Cancer Center , Cancer Center , Cutaneous Malignancy , Malignant Melanoma , Skin Cancer , Alignant Skin Neoplasm , Biologic Therapy , Alignant Neoplasia , Cancer Vaccine , Actinic Dermatoses , Ctinic Skin Damage , Sun Damaged Skin , Iological Marker , Computed Tomography ,

Researchers develop a new multi-omics microsampling method for complete health profiling

Researchers developed a multi-omics-based microsampling workflow for profiling proteins, metabolites, lipids, and specific cytokines and hormones, i.e., multiple analytes, in a single blood sample of 10 μl (microsample). ....

Aimee Molineux , Neha Mathur , Neha Mathurjan , Nature Biomedical Engineering , Discovery Industry Focus ,

Persistent tumor mutation burden linked with therapeutic response to immunotherapy

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy. ....

Noushin Niknafs , Valsamo Anagnostou , Johns Hopkins , Emily Henderson , Bloomberg Kimmel Institute For Cancer Immunotherapy , Johns Hopkins Kimmel Cancer Center , Lung Cancer Precision Medicine Center , Kimmel Institute , Johns Hopkins Molecular Tumor Board , Cancer Genome Atlas , Johns Hopkins Kimmel Cancer , Ancer Immunotherapy , Head And Neck Cancer , Immune Response , Immune System , Lung Cancer , Precision Medicine ,