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The substrate-binding domains of the osmoregulatory ABC importer OpuA physically interact

The substrate-binding domains of the osmoregulatory ABC importer OpuA physically interact
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What is the impact of cholesterol on SARS-CoV-2 Spike protein-mediated membrane fusion?

Researchers assessed the impact of ceramide (CER) and cholesterol (CHOL) on membrane fusion mediated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein. ....

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Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases
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2019-nCoV Spike Protein RBD (Y453F) : Get Quote, RFQ, Price or Buy

SignalChem’s Recombinant 2019-nCoV Spike protein S1 subunit, RBD (Y453F) (319-541), was expressed in CHO cells with a C-terminal His tag. The purity of the S1 subunit was found to be approximately 90% using densitometry and the molecular weight was roughly 39 kDa.
The activity of the S1 subunit has been detected by investigating the binding potential of the 2019-nCoV Spike protein RBD (Y453F) to the immobilized human ACE2 (19-740) protein with the help of a functional ELISA.
Scientific background
The SARS-CoV-2 spike glycoprotein’s receptor binding domain (RBD) identifies the host ACE2 receptor and is a crucial determinant of viral entry and neutralization, while being the most divergent region. ....

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