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The quarterfinals are set for April 21-22 and April 28-29, the semifinals for May 12-13 and May 19-20, and the dates of the two-leg final in June have not been announced.
Title-holders Wydad Casablanca of Morocco and Esperance of Tunisia won CAF Champions League groups early on Sunday, and set up a potential blockbuster quarter-finals clash with Al Ahly of Egypt.
Mamelodi Sundowns remain top of their CAF Champions League group after playing to a 2-2 draw against Al Ahly on Saturday night.
Real Madrid thumped Al Ahly 4-1 and progressed to the final of the FIFA Club World Cup on Wednesday night.
Democratic Republic of Congo giants TP Mazembe sacked French coach Franck Dumas on Saturday after a shock home loss to Ugandan side Vipers in a CAF Champions League qualifier.