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Operations to Accommodate Increasing Demand for Cell Analysis Solutions...

Science for just $15 USD. Short circuiting solid tumors Two major hurdles in chimeric antigen receptor (CAR) T cell therapy for solid tumors are ensuring specificity to tumor cells without affecting healthy cells and avoiding tumor escape due to antigen loss. To address these challenges, Hyrenius-Wittsten et al. and Choe et al. developed synthetic Notch (synNotch)–CAR T cells targeting solid tumor antigens and used them to treat mouse models of mesothelioma, ovarian cancer, and glioblastoma. In both studies, the authors demonstrated that synNotch-CAR T cells were better at controlling tum...

Rating: Application Area:Live cell imaging and analysis "The Incucyte SX5 is an easy-to-use live-cell imaging technology, saving our scientists time in both experimental set-up and monitoring whilst providing exceptional, previously unobtainable readouts. Protocols for a wide range of lab-based assays are freely available and easy to follow. Many of our scientists have already switched many of their traditional lab-based assays to use the Incucyte technology instead. The ability to monitor your cells in real-time remotely is a hugely attractive feature to our scientists especially d...

Rating: Application Area:Live cell imaging and analysis "The Incucyte SX5 is an easy-to-use live-cell imaging technology, saving our scientists time in both experimental set-up and monitoring whilst providing exceptional, previously unobtainable readouts. Protocols for a wide range of lab-based assays are freely available and easy to follow. Many of our scientists have already switched many of their traditional lab-based assays to use the Incucyte technology instead. The ability to monitor your cells in real-time remotely is a hugely attractive feature to our scientists especially d...