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Religious leaders in two cities say use of abortion-derived cells in development means believers should prefer Pfizer and Moderna Melissa Owens, operations plant manager for the McKesson Corporation, signs the first shipping box of the Johnson and Johnson Covid-19 vaccine in Shepherdsville, Kentucky, on Monday. Photograph: Timothy D Easley/EPA The archdiocese of New Orleans, as well as Roman Catholic leaders in St Louis, Missouri, have told local Catholics to avoid the Johnson & Johnson’s single-shot Covid-19 vaccine, because its early development used “morally compromised c...

High-Throughput Screening Market worth $26.4 billion by 2025 - Exclusive Report by MarketsandMarkets "High-Throughput Screening (HTS) Market by Product (Instruments, Software, Service), Technology (Cell-Based Assays, Label-Free), Application (Drug Discovery, Biochemical Screening, Research), End User (Pharma & Biotech, CROs)- Global Forecast to 2025", published by MarketsandMarkets, the global High-Throughput Screening Market size is projected to reach USD 26.4 billion by 2025 from USD 15.3 billion in 2020, at a CAGR of 11.5% during the forecast period. Browse in-depth TOC on Download PDF...

The HTS Market growth is driven mainly by factors such as increasing R&D spending by pharmaceutical & biotechnology companies, technological advancements in high-throughput screening market and the availability of government funding & venture capital investments. Emerging markets and growing applications in life sciences research are also factors expected to provide growth opportunities for players in the market. The consumables segment accounted for the largest share of the product & services segment in the high-throughput screening market in 2019. On the basis type of product & service, the...

F) normal. * P 0.05, Compared with moderately differentiated and poorly differentiated tissues, Sox2 mRNA was significantly higher in well-differentiated tissues. The Association of Sox2 Expression with Clinicopathological Parameters To further investigate the association between Sox2 expression and clinicopathological parameters. 60 samples were divided into two groups according to Sox2 staining intensity, including high Sox2 staining (n 19) and low Sox2 staining (n 41). We found the Sox2 expression had a strong association with depth of invasion (0.0011), lymph node metastasis (0.0013) and ...

New antibody discovery platform could help accelerate CAR-T therapeutic development In a paper published in the Journal of Biological Chemistry​​​, OXGENE scientists used the self-labelling integral membrane (SLIM) protein discovery system to identify a panel of novel antibodies against the oncogenic target epithelial cell adhesion molecule, which remained in its native configuration within the cell membrane. They said they were able to further demonstrate the functionality of these antibodies in killing cancer cells, when used as a targeting domain of CAR-T cells, thereby “validatin...