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New gene therapy trial in US offers hope for children with Canavan disease - Vimarsana News

New gene therapy trial in US offers hope for children with Canavan disease

0 shares Benny Landsman, 4, at Dayton Children’s Hospital April 8, 2021, before surgery to receive the first clinical trial of a new gene therapy for Canavan disease. (Courtesy of the Landsman family/ via Dayton Jewish Observer) Benny Landsman, 4, is prepped for surgery at Dayton Children’s Hospital, April 8, 2021. (Courtesy of the Landsman family/ via Dayton Jewish Observer) Benny Landsman with Paola Leone and Dr. Christopher G. Janson at Dayton Children’s Hospital, April 8, 2021. (Courtesy of the Landsman family/ via Dayton Jewish Observer) Jordana Holovach with her late son, Ja...

Gene Therapy Trial Offers Hope for Children With Canavan - Vimarsana News

Gene Therapy Trial Offers Hope for Children With Canavan

By Marshall Weiss, The Dayton Jewish Observer (reprinted with permission) | May 06, 2021 In an operating room at Dayton Children’s Hospital on April 8, 4-year-old Benny Landsman of Brooklyn received the first new clinical trial of an FDA-approved gene therapy for Canavan disease. Neurosurgeon Dr. Robert Lober placed four catheters in holes drilled into Benny’s skull, down a track to a fluid space in the brain’s ventricles. Lober then manually injected a fluid containing 370 trillion viral genomes of the new therapy. By his side in the operating room were the trial’s cli...