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Non–Clear Cell RCC Subtypes Require Individualized Approach to Treatment Selection

Jaime R. Merchán, MD, spotlights case studies of patients with rare non-ccRCC histologies, discussing their clinical presentation, recent data on immunotherapy and targeted treatment options for the management of these disease subtypes, and patient outcomes on these therapies.

University-of-miami , Florida , United-states , Jaimer-merch , Department-of-medicine , National-cancer-institute , University-of-miami-health-system , National-comprehensive-cancer-network , Division-of-medical-oncology , Clinical-oncology-research-program , Science-summit

Frontline IO/TKI Regimens Continue to Evolve in ccRCC

Jaime R. Merchán, MD, discusses the evolution and current role of IO/TKI regimens in advanced RCC; highlights data from the phase 3 CLEAR and KEYNOTE-426 trials supporting the use of pembrolizumab-based regimens in untreated ccRCC; and speculates on how future biomarker-driven research could improve the benefit seen with these combinations in this disease.

Florida , United-states , University-of-miami , Jaimer-merch , Clinical-oncology-research-program , Division-of-medical-oncology , Department-of-medicine , University-of-miami-health-system , Science-summit , Medical-oncology , Trials-program

Whole genome sequencin provides clearest picture of the genetic changes leading to Hodgkin lymphoma

To create the most effective, personalized treatment plans for patients with Hodgkin lymphoma or other cancers, scientists and clinicians need the clearest picture of the genetic changes leading to the cancer's development.

Miami , Florida , United-states , Miller-school , American , C-ola-landgren , Craig-moskowitz , Francesco-maura , Reed-sternberg , Lisa-giulino-roth , Emily-henderson , Oncology-service-line-at-sylvester

Research Shows Whole Genome Sequencing Offers Unprecedented Look at Hodgkin Lymphoma Genetics

Research Shows Whole Genome Sequencing Offers Unprecedented Look at Hodgkin Lymphoma Genetics
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Miami , Florida , United-states , Miller-school , University-of-miami , American , Weill-cornell , C-ola-landgren , Craig-moskowitz , Francesco-maura , Reed-sternberg , Lisa-giulino-roth

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

Miami , Florida , United-states , C-ola-landgren , Benjamin-diamond , Francesco-maura , Emily-henderson , Sylvester-myeloma-research-institute , Myeloma-genomic-lab-at-sylvester , Myeloma-research-institute , Scientists-at-sylvester-comprehensive-cancer-center , Clinical-oncology-research-program