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Catheter Ablation for AFib Shows Little to No Benefit in HFpEF, Despite Positive Effect in HFrEF

A meta-analysis of 12 trials suggests catheter ablation for atrial fibrillation reduces heart failure events in HFrEF patients but not in HFpEF.

Kristen-patton , Clyde-yancy , Alireza-oraii , Linkedin-alireza-oraii , University-of-washington , Northwestern-university , York-heart-association , Penn-medicine , Cochrane-central-register , Controlled-trials , New-york-heart-association , Standard-deviation

Statins slightly up diabetes risk but cardiovascular benefits remain, finds study

Statin therapy modestly increases diabetes diagnoses but offers substantial cardiovascular benefits, outweighing the slight rise in glycemia, especially in those near diabetes diagnostic thresholds.

Roger-ashford , Lancet-diabetes , Image-credit , Cochrane-central-register , Controlled-trials , Cholesterol-treatment-trialist , Medical-dictionary , Regulatory-activities , Diabetes , Lood , Ardiovascular-disease

Dose-Escalation, Low-Dose Regimens May Improve Roflumilast Treatment Adherence in Patients With COPD

This study suggests that dose-escalation or low-dose regimens for roflumilast treatment in patients with chronic obstructive pulmonary disease (COPD) may improve adherence.

South-korea , Republic-of-korea , Ivelin-radkov , International-journal-of-chronic-obstructive-pulmonary-disease , International-journal , Chronic-obstructive-pulmonary , Image-credit , Cochrane-central-register ,

"Multimodal Analgesic Effectiveness on Acute Postoperative Pain Managem" by Rochelle Wynne, Suzanne Fredericks et al.

Background Many patients report moderate to severe pain in the acute postoperative period. Enhanced recovery protocols recommend multimodal analgesics, but the optimal combination of these is unknown. Purpose The aim of this study was to synthesize the best available evidence about effectiveness of multimodal analgesics on pain after adult cardiac surgery. Methods A systematic review to determine the effect of multimodal postoperative analgesics is proposed (International Prospective Register of Systematic Reviews Registration CRD42022355834). Multiple databases including the Cochrane Library, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, American Psychological Association, the Education Resources Information Centre, the Excerpta Medica database, the Medical Literature Analysis and Retrieval System Online, Scopus, Web of Science, and clinical trials databases will be searched. Screening in Covidence and quality assessment will be conducted by 2 authors. A grading of recommendations, assessment, development, and evaluation summary of findings will be presented if meta-analysis is possible.

United-states , American , Cochrane-library , Education-resources-information-centre , American-psychological-association , International-prospective-register-of-systematic-reviews-registration , Health-literature , International-prospective-register , Systematic-reviews-registration , Cochrane-central-register , Controlled-trials

"Effects of eHealth Interventions on 24-Hour Movement Behaviors Among P" by Shan Jiang, Johan Y.Y. Ng et al.

BACKGROUND: The high prevalence of unhealthy movement behaviors among young children remains a global public health issue. eHealth is considered a cost-effective approach that holds great promise for enhancing health and related behaviors. However, previous research on eHealth interventions aimed at promoting behavior change has primarily focused on adolescents and adults, leaving a limited body of evidence specifically pertaining to preschoolers. OBJECTIVE: This review aims to examine the effectiveness of eHealth interventions in promoting 24-hour movement behaviors, specifically focusing on improving physical activity (PA) and sleep duration and reducing sedentary behavior among preschoolers. In addition, we assessed the moderating effects of various study characteristics on intervention effectiveness. METHODS: We searched 6 electronic databases (PubMed, Ovid, SPORTDiscus, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials) for experimental studies with a randomization procedure that examined the effectiveness of eHealth interventions on 24-hour movement behaviors among preschoolers aged 2 to 6 years in February 2023. The study outcomes included PA, sleep duration, and sedentary time. A meta-analysis was conducted to assess the pooled effect using a random-effects model, and subgroup analyses were conducted to explore the potential effects of moderating factors such as intervention duration, intervention type, and risk of bias (ROB). The included studies underwent a rigorous ROB assessment using the Cochrane ROB tool. Moreover, the certainty of evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) assessment. RESULTS: Of the 7191 identified records, 19 (0.26%) were included in the systematic review. The meta-analysis comprised a sample of 2971 preschoolers, which was derived from 13 included studies. Compared with the control group, eHealth interventions significantly increased moderate to vigorous PA (Hedges g=0.16, 95% CI 0.03-0.30; P=.02) and total PA (Hedges g=0.37, 95% CI 0.02-0.72; P=.04). In addition, eHealth interventions significantly reduced sedentary time (Hedges g=-0.15, 95% CI -0.27 to -0.02; P=.02) and increased sleep duration (Hedges g=0.47, 95% CI 0.18-0.75; P=.002) immediately after the intervention. However, no significant moderating effects were observed for any of the variables assessed (P>.05). The quality of evidence was rated as "moderate" for moderate to vigorous intensity PA and sedentary time outcomes and "low" for sleep outcomes. CONCLUSIONS: eHealth interventions may be a promising strategy to increase PA, improve sleep, and reduce sedentary time among preschoolers. To effectively promote healthy behaviors in early childhood, it is imperative for future studies to prioritize the development of rigorous comparative trials with larger

Cochrane-central-register , Controlled-trials , Recommendations-assessment ,

"The Relationship between Transformational Leadership and Staff Nurse R" by Nathalie Conroy, Declan Patton et al.

Aim. This systematic review aimed to synthesise the relationship between transformational leadership style and staff nurse retention in hospital settings. Background. It is known that globally there is a shortage of nurses. Thus, nurse retention and organisational commitment have never been more critical. Nurse managers are responsible for staff retention. Therefore, nurse managers could reduce staff turnover by adopting the "right leadership style."Methods. Systematic review, following the guidance of PRISMA. Databases CINAHL, MEDLINE, PubMed, PsychInfo, Cochrane Central Register, and Embase were searched between 27th December 2021 and 22nd June 2023 to find relevant publications. Relevant studies were hand searched in January 2022 and June 2023 to source further potential evidence. A total of twelve articles were retrieved. Results. Twelve studies were included in this review, including six cross-sectional studies, two correlational studies, two cross-sectional correlational studies, and two surveys. In relation to retention, the primary outcome, data from eleven of the twelve studies reported statistical significance favouring transformational leadership improving staff retention. One study reported a statistically nonsignificant improvement in retention. Conclusion. There is evidence to suggest that transformational leadership may have a positive and significant relationship with staff nurse retention, job satisfaction, and quality of care. Implications for Nursing Management. Nurse managers should attend leadership and management training programs. This will allow them to understand and practice transformational leadership which may have a positive connection with staff nurse retention.

Cochrane-central-register ,

Digital Gamification Tools to Enhance Vaccine Uptake: Scoping Review

Digital Gamification Tools to Enhance Vaccine Uptake: Scoping Review
comminit.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from comminit.com Daily Mail and Mail on Sunday newspapers.

Julien-chevrier , Dominique-gagnon , Polytechnique-montr , S-michelle-driedger , Hollyo-witteman , Global-health , University-of-manitoba-driedger , Google , Science-core-collection , Cochrane-database , Systematic-reviews , Cochrane-central-register

Strength Training Safely Boosts Muscular Dystrophy Outcomes, but Further Study Needed

Data are scarce regarding the benefits of strength training for muscular dystrophies, for which there are no cures.

Cochrane-central-register , Controlled-trials , Image-credit , Facioscapulohumeral-dystrophy- , Conservative-nonpharmacological-treatmen , Muscular-dystrophies ,

CD4/CD8 Ratio a Useful Predictor of Mortality in Patients Living With HIV

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings.

Ezume-images , Cochrane-central-register , Controlled-trials , Cd4 , Cd8 , Ratio , Mortality , Hiv ,

AGA Supports Fecal Microbiota-Based Therapies for C Diff in New Guideline

The guideline recommends fecal microbiota transplant in most cases of recurrent Clostridioides difficile infection but does not suggest fecal microbiota-based therapies for IBD or IBS.

United-states , American , Amanda-kabage , Anne-peery , University-of-north-carolina-school-medicine , American-gastroenterological-association , School-of-medicine-anne-peery , North-carolina-school , Cochrane-central-register , Controlled-trials , Cochrane-database , Systematic-reviews