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AI in healthcare shows promise in trials but needs real-world testing to ensure effectiveness

A comprehensive study published in The Lancet Digital Health analyzed the efficacy and challenges of AI in clinical settings, revealing a critical need for real-world testing and diverse research methodologies to ensure AI's reliable integration into healthcare.

United-states , China , International-clinical-trials-registry-platform , International-prospective-register-of-systematic-reviews , Lancet-digital-health , Drug-administration , Preferred-reporting-items , Systematic-reviews , International-prospective-register , Covidence-review , Google-sheets

Mediterranean diet linked to lower dementia risk, finds extensive review

Meta-analysis reveals a positive link between adherence to the Mediterranean diet and a reduced risk of dementia, particularly Alzheimer's disease, among older adults, highlighting the diet's potential as a modifiable risk factor in dementia prevention strategies.

Ottawa , Ontario , Canada , Australia , Experimental-research , International-prospective-register-of-systematic-reviews , Aging-clinical , Image-credit , Cochrane-preferred-reporting-items , Systematic-reviews , Meta-analysis-of-observational-studies

"Multimodal Analgesic Effectiveness on Acute Postoperative Pain Managem" by Rochelle Wynne, Suzanne Fredericks et al.

Background Many patients report moderate to severe pain in the acute postoperative period. Enhanced recovery protocols recommend multimodal analgesics, but the optimal combination of these is unknown. Purpose The aim of this study was to synthesize the best available evidence about effectiveness of multimodal analgesics on pain after adult cardiac surgery. Methods A systematic review to determine the effect of multimodal postoperative analgesics is proposed (International Prospective Register of Systematic Reviews Registration CRD42022355834). Multiple databases including the Cochrane Library, Cochrane Central Register of Controlled Trials, Cumulative Index to Nursing and Allied Health Literature, American Psychological Association, the Education Resources Information Centre, the Excerpta Medica database, the Medical Literature Analysis and Retrieval System Online, Scopus, Web of Science, and clinical trials databases will be searched. Screening in Covidence and quality assessment will be conducted by 2 authors. A grading of recommendations, assessment, development, and evaluation summary of findings will be presented if meta-analysis is possible.

United-states , American , Cochrane-library , Education-resources-information-centre , American-psychological-association , International-prospective-register-of-systematic-reviews-registration , Health-literature , International-prospective-register , Systematic-reviews-registration , Cochrane-central-register , Controlled-trials

Diets impact Parkinson's motor symptoms, supplements show no benefit, study finds

Meta-analysis reveals that diets like the Mediterranean and ketogenic can improve motor function in Parkinson's disease patients, although dietary supplements do not enhance UPDRS or 6MWT scores.

Wanfang , Jiangxi , China , Weipu , Fujian , Cochrane-library , International-prospective-register-of-systematic-reviews , International-parkinson , Movement-disorder-society , China-national-knowledge-infrastructure , European-journal

How does intermittent fasting affect the gut microbiome?

Review examines the effects of intermittent fasting (IF) on the human gut microbiome, revealing variable impacts on microbiota composition and diversity, influenced by fasting type, dietary habits, and individual microbiome characteristics.

Tatiana-shepeleva , Rayyan-qatar-computing-research-institute , International-prospective-register-of-systematic-reviews , Preferred-reporting-items , Systematic-reviews , International-prospective-register , Fasting , Icrobiome , Nti-inflammatory , Lood , Lood-pressure , Iet

Global study reveals varied intention to receive monkeypox vaccine: 61% prevalence worldwide

The global prevalence and regional differences in the intention to receive the monkeypox.

United-states , American , International-prospective-register-of-systematic-reviews , Public-health , Joanna-briggs-institute-meta , Image-credit , International-prospective-register , Systematic-reviews , Preferred-reporting-items , Joanna-briggs-institute-meta-analysis , Statistics-assessment

Effectiveness of environmental interventions in managing autism

Researchers evaluate the health-related outcomes of nature-based interventions in children with autism.

Mama-belle , International-prospective-register-of-systematic-reviews , Health-literature , World-health-organization , Nature-based-interventions , Autistic-children , Systematic-review , Image-credit , Preferred-reporting-items , Systematic-reviews , International-prospective-register , Cumulative-index

The association between hypertensive disorders of pregnancy and subsequent risk of dementia

Researchers examined the link between hypertensive disorders of pregnancy (HDP) and the increased risk of dementia, utilizing a systematic review and meta-analysis approach to cohort studies.

Henadzipechan-shutterstock , International-prospective-register-of-systematic-reviews , Hypertension-research , Preferred-reporting-items , Systematic-reviews , International-prospective-register , Dementia , Regnancy , Lzheimer-39s-disease , Lood , Lood-pressure , Clampsia

Switching from animal-based to plant-based foods reduces risk of heart disease, diabetes, and mortality

The effects of replacing animal-based foods with plant-based alternatives on cardiometabolic health and all-cause mortality.

United-states , Antonina-vlasova-shutterstock , International-prospective-register-of-systematic-reviews , International-prospective-register , Systematic-reviews , Preferred-reporting-items , Non-randomized-studies , Diabetes , Eart , Eart-disease , Ortality , Utter

Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder?

Researchers assessed the efficacy and compared the relative effectiveness of various pharmacological treatments for alcohol use disorder.

United-states , Americans , Cochrane-library , International-prospective-register-of-systematic-reviews , Peer-review-of-electronic-search-strategies , Drug-administration , Alcohol-use-disorder , Systematic-review , Image-credit , International-prospective-register , Systematic-reviews