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Solanezumab does not slow cognitive decline in patients with Alzheimer's disease

1. In this randomized controlled trial, over a period of 240 weeks, solanezumab did not slow cognitive decline as compared to placebo in patients with preclinical Alzheimer’s disease. 2. Solanezumab did not change the levels of amyloid levels in the brain as compared to placebo in persons with preclinical Alzheimer’s disease. Evidence Rating Level: 1 (Excellent) ....

Minute Medicine Inc , Rating Level , Mild Dementia Due , Clinical Dementia Rating , Mental State Examination , Preclinical Alzheimer , Cognitive Composite , Alzheimer 039 S , Alzheimers Disease , Chronic Disease ,

Self-Reflection Linked to Improved Late-Life Cognition and Brain Health

A person's ability to self-reflect is associated with cognition and glucose metabolism later in life, a new study finds. Those who engage in more self-reflection had improved cognition, better overall brain health, and increased glucose metabolism later in life. ....

United Kingdom , Richard Oakley , Harriet Demnitz King , Brain Health In Cognitively Unimpaired Older Adults , Research At Alzheimer Society , Association Between Self , Natalie Marchant , Associate Director , Chris Lane , Between Self Reflection , Brain Health , Cognitively Unimpaired Older , Rumination Response Scale , Preclinical Alzheimer , Cognitive Composite , Neuroscience Newsletter ,