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Antibody binding-site conserved across COVID-19 virus variants

Antibody binding-site conserved across COVID-19 virus variants
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Antibody binding-site conserved across COVID-19 virus variants

Date Time
Antibody binding-site conserved across COVID-19 virus variants
A Penn State research team found that the N protein on SARS-CoV-2 is conserved across all SARS-related pandemic coronaviruses (top, from left: SARS-CoV-2, civet, SARS-CoV, MERS). The protein differs from other coronaviruses, such as those that cause the common cold (bottom, from left: OC43, HKU1, NL63 and 229E).
Image: Kelly Lab/Penn State
A tiny protein of SARS-CoV-2, the coronavirus that gives rise to COVID-19, may have big implications for future treatments, according to a team of Penn State researchers.
Using a novel toolkit of approaches, the scientists uncovered the first full structure of the Nucleocapsid (N) protein and discovered how antibodies from COVID-19 patients interact with that protein. They also determined that the structure appears similar across many coronaviruses, including recent COVID-19 variants – making it an ideal target for advanced treatments and vaccines. The ....

South Africa , United States , United Kingdom , Williamy Luqiu , Mariah Schroen , Jared Wilson , Deb Kelly , Michael Casasanta , Williamj Dearnaley , Mariaj Solares , Penn State Center , Integrative Biosciences Graduate Program , Penn State Materials Research Institute , Computer Engineering At Duke University , Department Of Electrical , Protochips Inc , Huck Institutes Of The Life Sciences , Penn State , Huck Chair , Molecular Biophysics , Structural Oncology , Raybiotech Life , Direct Electron , Materials Research Institute , Genomics Graduate Program , Huck Institutes ,

Worst Case Scenarios: AI | Penn Today

Worst Case Scenarios: AI
Mary Missy Cummings, professor in the department of Electrical and Computer Engineering at Duke University, and Paul Scharre, Senior Fellow and Director of the Technology and National Security Program at the Center for a New American Security, discuss potential dangers of artificial intelligence and how to navigate these challenges through global policy.
For more information, visit global.upenn.edu.
Tuesday, February 09, 2021 ....

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