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This systematic review to support the 2022 US Preventive Services Task Force Recommendation Statement on vitamin and mineral supplements for the prevention of c
Low-dose aspirin is used to prevent primary cardiovascular disease and may be beneficial in the prevention of colorectal cancer. Learn more.
The temporal evolution of SARS-CoV-2 vaccine efficacy and effectiveness (VE) against infection, symptomatic, and severe COVID-19 is incompletely defined. The temporal evolution of VE could be dependent on age, vaccine types, variants of the virus, and geographic region. We aimed to conduct a systematic review and meta-analysis of the duration of VE against SARS-CoV-2 infection, symptomatic COVID-19 and severe COVID-19. MEDLINE, Scopus, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, the World Health Organization Global Literature on Coronavirus...
Noelle Le Tourneau and co-workers study HIV outcomes in studies investigating reduced frequency of antiretroviral drug provision and clinical consultations.
Author summary Why was this study done? Sustained engagement and retention in HIV care is critical for optimal HIV treatment outcomes and reduced HIV transmission. For many people living with HIV, disengagement is inevitable during the long course of HIV treatment. It remains unclear which combination of reengagement strategies are most effective and under what conditions. What did the researchers do and find? Our systematic review identified 37 studies (6 randomized trials and 31 observational studies), 16 of which were conducted in low- and middle-income countries. The majority of rand...