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Brushing also tied to decreased ICU mortality, need for mechanical ventilation

Recent meta-analyses of the efficacy of second-generation antidepressants for youth have concluded that they possess anadvantage over placebo in terms of clinician-rated depressive symptoms, but no meta-analysis has included measures of quality of life, global mental health, self-esteem, or autonomy.

Objective We explored the comparative effectiveness of available therapies for chronic pain associated with temporomandibular disorders (TMD). Design Systematic review and network meta-analysis of randomised clinical trials (RCTs). Data sources MEDLINE, EMBASE, CINAHL, CENTRAL, and SCOPUS were searched to May 2021, and again in January 2023. Study selection Interventional RCTs that enrolled patients presenting with chronic pain associated with TMD. Data extraction and synthesis Pairs of reviewers independently identified eligible studies, extracted data, and assessed risk of bias. We captured ...

Pancreatic cancer remains among the malignancies with the worst outcomes. Survival has been improving, but at a slower rate than other cancers. Multimodal treatment, including chemotherapy, surgical resection, and radiotherapy, has been under investigation for many years. Because of the anatomical characteristics of the pancreas, more emphasis on treatment selection has been placed on local extension into major vessels. Recently, the development of more effective treatment regimens has opened up new treatment strategies, but urgent research questions have also become apparent. This review outl...

Adding a GLP-1 receptor agonist like liraglutide to endoscopic bariatric therapy produces significant weight loss results.