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Treatment Modalities of Hemorrhoidal Disease

Hemorrhoidal disease (HD) is a form of an anorectal disease characterized by symptomatic enlargement and/or distal displacement of the healthy anal cushions known as hemorrhoids (1). Alarmingly, one. ....

United States , Journal Of Comparative Effectiveness Research , French National Society Of Coloproctology , American Gastroenterological Association , Association Of Colon Rectal Surgeons India , Hemorrhoidal Disease , Look Into Current Therapies , Unique Mechanism , Acute Episodes , French National Society , Rectal Surgeons , World Piles Day , Vouch To Strike , Comparative Effectiveness Research , Database Syst Rev , Surgical Management , Badrul Hisham , Complement Ther Med , World Piles Day 2022 , Hemorrhoid Treatment ,

Type 2 diabetes

Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of
diabetes worldwide. The number affected is increasing rapidly with alarming trends
in children and young adults (up to age 40 years). Early detection and proactive management
are crucial for prevention and mitigation of microvascular and macrovascular complications
and mortality burden. Access to novel therapies improves person-centred outcomes beyond
glycaemic control. Precision medicine, including multiomics and pharmacogenomics,
hold promise to enhance understanding of disease heterogeneity, leading to targeted
therapies. ....

United Kingdom , United States , City Of , Mosalman Haghighi , Fiatarone Singh , Cardiovasc Diabetol , Endocrinol Lausanne , Van Rhoon , J Clin Endocrinol , Gurushantappa Mangshetty , Clin Nutr , Pharmaceuticals Basel , Diabetes Prevention Program Outcomes Study , American College Of Sports Medicine , J Phys Act Health , American Diabetes Association , Health Qual Life Outcomes , Health Utility Index , Department Of Health Social Care , Intj Environ Res Public Health , Digit Health , Study Research Group , Health Promot Int , European Association For The Study Of Diabetes , Diabetes Prevention Program , National Institute For Health ,

Phase 2 data on a new treatment for hot flushes in women with breast cancer

Bothersome vasomotor symptoms (ie, hot flashes or flushes and night sweats) are common
after breast cancer, sometimes aggravated by chemotherapy-induced premature menopause
or adjuvant endocrine treatments. Consequently, there is a long history of clinical
trials testing a variety of centrally acting agents, including selective serotonin
reuptake inhibitors, selective norepinephrine reuptake inhibitors, gabapentin, and
others,1,2 to manage vasomotor symptoms when menopausal oestrogen therapy (transdermal
or oral oestrogens) is contraindicated. ....

Amanda Vrselja , Database Syst Rev , Natl Cancer Inst ,

Transfusion practice in patients receiving VV ECMO (PROTECMO): a prospective, multicentre, observational study

During VV ECMO, there was no universally accepted threshold for transfusion, but PRBC
transfusion was invariably associated with lower mortality only when done with haemoglobin
concentration of less than 7 g/dL. ....

New York , United States , J Cardiothorac Vasc Anesth , European Society Of Intensive Care Medicine , Extracorporeal Life Support Organization , Extracorporeal Life Support Organization Registry , Canadian Critical Care Trials Group , Scare Med , Intensive Care Med , Database Syst Rev , European Society , Intensive Care , Thorac Surg , Critical Care Investigators , Canadian Critical Care Trials , Englj Med , Cardiothorac Vasc Anesth , Thorac Dis ,

How to Treat: Subfertility

All GPs have patients with fertility problems who, at some point, may need advice, investigations organised and appropriate referral. This article, written by Olivia Stuart, provides an overview of the optimal lifestyle and medical advice for men and women, discusses the best predictors of fertility, and presents the relevant investigations and latest treatment options ....

South Australia , New Zealand General , New Zealand , United States , New Providence , Reprod Genet , Van Velzen , Van Wely , Edcs Health , Endocrine Society , Monash University , World Health Organization , Monash University International , American Thyroid Association , Buck Louis , Assist Reprod Genet , University International , American Society , Database Syst Rev , Clin Endocrinol Metab , Health Organization , Biomed Online ,