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Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins.

MEDINA — No one could be prouder of his military service than Jim Freas, and now he has more reason to be proud.

When Pittsburgh police charged Tyler Sherrell with homicide, claiming he was the getaway driver in a fatal shooting, the only evidence they had was the self-serving word of the man who orchestrated the hit. Matthew Lambert waited two years after his arrest before giving detectives Sherrell’s name. He met with

Allegheny County court officials are still trying to figure out how a man accused of carrying $1.6 million in fentanyl in Pittsburgh was released from custody this month, and now another judge is reportedly involved in the snafu. A nationwide arrest warrant was issued for Yan Carlos Pichardo Cepeda, 27,

Over the next several months, as the trial unfolds in connection with the Squirrel Hill synagogue shooting, Pittsburgh will be repeatedly reminded that it is home to the worst antisemitic attack in U.S. history. Eleven people from three congregations — Tree of Life-Or L’Simcha, Dor Hadash and New Light —