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Blocking Immune Molecule Slows Aggressive Childhood Cancer

Blocking Immune Molecule Slows Aggressive Childhood Cancer
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Marta Alonso , Iker Ausejo Mauleon , Cima Solid Tumor Program , Pablo Ugarte Association , Cancer Center Cl , Spanish Association Against Cancer , European Research Council , Cima Cancer Division , Adey Foundation , Universidad De Navarra , Diffuse Midline Glioma ,

Blocking immune molecule reduces tumor growth, prolongs survival of most aggressive childhood cancer in animal models

Blocking immune molecule reduces tumor growth, prolongs survival of most aggressive childhood cancer in animal models
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Iker Ausejo Mauleon , Marta Alonso , Cima Solid Tumor Program , Cima Cancer Division , Cancer Cell , Universidad De Navarra , Diffuse Midline Glioma ,

Blocking TIM-3 checkpoint molecule promotes antitumor immune response in diffuse intrinsic stem glioma

Researchers from Cima and the Clínica Universidad de Navarra, together with the international cooperative group Diffuse Midline Glioma (DMG-ACT), have confirmed that blocking an immune checkpoint molecule reduces the tumor and prolongs survival in animal models of the most aggressive childhood cancer. This research, carried out at the Cancer Center Clínica Universidad de Navarra, shows that inhibition of TIM-3 promotes the immune memory of diffuse intrinsic stem glioma (DIPG) and improves the prognosis of the disease. ....

Lily Ramsey , Marta Alonso , Iker Ausejo Mauleon , Cancer Center Cl , Cima University Of Navarra , European Research Council , Cima Solid Tumor Program , Spanish Association Against Cancer , Adey Foundation , Pablo Ugarte Association , Cima Cancer Division , Universidad De Navarra , Diffuse Midline Glioma , Cima University , Cima Solid Tumor , Immune Response ,