Genome haplarithmisis sheds light on complex genetic landscape of miscarriages
A new study published in Nature Medicine reports on a chromosomal analysis of over 1,700 spontaneous early miscarriages.
Source: news-medical.net
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Study sheds light on origins of breast cancer in people with BRCA2 mutations
A pioneering study led by Professor Ashok Venkitaraman from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and Dr Mona Shehata from the University of Cambridge (UK) has uncovered vital insights into the distinct effects of BRCA2 mutations on breast tissue cells, shedding light on early breast cancer development in people with BRCA2 mutations.
Source: news-medical.net
New PCNA inhibitor AOH1996 shows selective cancer cell killings and tumor suppression potential
Study described a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) that selectively kills cancer cells.
Source: news-medical.net
City of Hope tests promising new 'killer-pill' cancer treatment
Los Angeles-based City of Hope researchers have developed a new chemotherapy pill that appears to kill all solid tumors.
Source: beckershospitalreview.com
Phase 1 clinical trial underway to test City of Hope-developed cancer treatment
Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too challenging for targeted therapy, proliferating cell nuclear antigen (PCNA), and developed a targeted chemotherapy that appears to annihilate all solid tumors in preclinical research.
Source: news-medical.net