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Unzipping mRNA rallies plant cells to fight infection

Unzipping mRNA rallies plant cells to fight infection
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Xinnian Dong , Yezi Xiang , Us National Institutes Of Health , Key Research Development Program Of China , Dong Lab , Natural Science Foundation Of China , Us National Science Foundation , Howard Hughes Medical Institute , Duke University Led , Science Foundation , State Key Research Development Program , Natural Science Foundation ,

P2X7R in Mast Cells is a Potential Target for Salicylic Acid and Aspir


7 P2X receptors carry out many important functions in the central and peripheral nervous system.
8,9 Compelling evidence has shown that P2X3, P2X4 and P2X7 receptors are involved in the pathogenesis of chronic pain.
10 P2X7R exists in neurons and glial cells of the nervous system, but is mainly expressed in cells of immune origin such as monocytes, macrophages, and microglia.
11 The absence of P2X7R can completely eliminate the inflammatory and neuropathic hypersensitivity to both mechanical and temperature stimulation.
12–14 P2X7R in microglia plays an important role in chronic neuropathy and inflammatory pain by releasing pro-inflammatory cytokines such as IL-1β. ....

United States , Johns Hopkins , Tocris Bioscience , Research Collaboratory , Shanghai Institute Of Biochemistry , China Pharmaceutical University , Dong Lab , Protein Data Bank , Molecular Devices Inc , Committee Of Nanjing University Chinese Medicine , A Molecular Devices Inc , Animal Care , Use Committee , Nanjing University , Chinese Medicine , Alomone Labs , Vazyme Biotech , Taq Mastermix , Master Mix , Assay Kit , Yuanye Biotech , Rabbit Anti P , Mouse Peritoneal Mast Cell , Shanghai Institute , Genscript Biotech , Cell Current Clamp Recordings ,