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Migrant Pathology Screening in the Pediatric Population: A Five-Year Retrospective Study From a Level II Hospital.

The migrant population residing in Portugal has been growing. In 2015, the pediatrics department at Professor Doutor Fernando Fonseca Hospital, a level II hospital, implemented a screening for endemic pathologies in asymptomatic migrant children to enable their timely diagnosis and treatment. This study aimed to identify and characterize the main findings in the migrant pathology screening.This was ....

Cape Verde , Guinea Bissau , Castello Branco Ribeiro , Doutor Fernando Fonseca , Doutor Fernando Fonseca Hospital ,

Systemic treatment for brain metastasis in HER2-positive advanced breast cancer

Systemic treatment for brain metastasis in HER2-positive advanced breast cancer
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Doutor Fernando Fonseca , Javier Cort , Marta Vaz Batista , Antonio Llombart , Medica Scientia Innovation Research , Maria Gion , Sofia Braga , Hospital Professor Doutor Fernando Fonseca , Human Epidermal ,

Cureus | Association of Tumor-Infiltrating Lymphocytes With Survival in Stages II and III Colorectal Cancer

The tumor microenvironment is crucial in tumourigenesis, response to therapy, and elimination of tumor cells. Tumor-infiltrating lymphocytes (TILs) promote the host immune response and are associated with a better prognosis in colorectal cancer (CRC). This multicentric retrospective study evaluated the relationship between the presence and intensity of TILs and survival outcomes. A total of 651 patients from four Portuguese oncological centers who underwent surgical resection for stages II or III colorectal adenocarcinoma between 2016 and 2019 were included in this study. The mean age of the study population was 70 years; 58.2% were males. The median overall survival was 58.03 ± 1.29 months (95% confidence interval (CI) 55.50 - 60.56), and the median disease-free survival (DFS) was 53.02 ± 1.39 months (95% CI 50.29 - 55.74). Patients with high infiltrate (including those with moderate, abundant, or Crohn-like infiltrate) had significantly longer DFS i.e., 58.48 ± 1.84 months (95% ....

United States , Doutor Fernando Fonseca , Royal College Of Pathologists , College Of American Pathologists , Statistical Package For The Social Sciences , International Tils Working Group , Hospital Professor Doutor Fernando Fonseca , Centro Hospitalar Lisboa Ocidental , Hospital Beatriz , Edition American Joint Committee , Cancer Staging Manual , Working Group , Statistical Package , Social Sciences , Ethical Committee , American Pathologists , Royal College ,