Unraveling the mystery of misfolded proteins in the brain
Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, s
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Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, s
PlatyBrowser combines different datasets to explore links between cell morphology and gene expression in Platynereis dumerilii juveniles Conceptual
E-Mail IMAGE: (a) A Cropped FRIL image used for input (b) Ground truth image annotated by human experts (c) Network-generated image with annotations d. Discriminator network to discern between real and fake images.... view more Credit: Max Planck Florida Institute for Neuroscience From sample preparation to image acquisition, electron microscopy (EM) requires precise and time-consuming steps to produce the clarity and detail needed to visualize small cell structures with high resolution. Moreover, once EM images are created, extracting the biological information out of them thro...
Novel method reveals the synaptic basis for feature selectivity A common analogy used to describe the brain is that it consists of tiny interconnected computers. Each one of these computers, or neurons, process and relay activity from thousands of other neurons, forming complex networks that allow us to perceive our surroundings, make decisions, and guide our actions. Communication between neurons occurs through tiny connections called synapses, and each neuron integrates the activity across these synapses to form a single output signal. However, not all synapses are created equal. Synapses c...
E-Mail IMAGE: Multiphoton imaging in vivo provides measures of synaptic activity and function (left), while electron microscopy (right) performed on the same neuron provides structural information at the nanometer scale view more Credit: Max Planck Florida Institute for Neuroscience A common analogy used to describe the brain is that it consists of tiny interconnected computers. Each one of these computers, or neurons, process and relay activity from thousands of other neurons, forming complex networks that allow us to perceive our surroundings, make decisions, and guide our acti...