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How cell identity is preserved when cells divide

A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation. Within each cell’s nucleus, MIT researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications. ....

Leonid Mirny , Alexander Grosberg , Dino Osmanovi , National Human Genome Research Institute , National Science Foundation , Institute For Medical Engineering , York University , National Institute , Department Of Physics , Jeremy Owen Phd , Medical Engineering , Living Systems , New York University , General Medical Sciences , National Science , Epigenetic Memory , Cell Fate , D Genome Structure , Ene Control , Leonid Mirny , Jeremy Owen , Dino Osmanovic ,

New research from The Jackson Laboratory and Weill Cornell Medicine: Severe COVID-19 can alter long-term immune system response

/PRNewswire/ Severe COVID-19 triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body s immune. ....

Steven Josefowicz , Duygu Ucar , Jin Gyu Cheong , Jackson Laboratory For Genomic Medicine , Jackson Laboratory , Weill Cornell Medicine , Genomic Medicine , Epigenetic Memory , Innate Immune Cells , Their Progenitors , Weill Cornell Medicine Immunology , Microbial Pathogenesis , The Jackson Laboratory ,

Severe COVID-19 leaves epigenetic immune system memory

A study from Weill Cornell Medicine and The Jackson Laboratory has described the epigenetic mark SARS-CoV-2 left on immune system stem cells in the most severe cases of COVID-19 early in the pandemic, before the development of vaccines. ....

Steven Josefowicz , Jackson Laboratory , Weill Cornell Medicine , Covid 19 , Sars Cov 2 , Epigenetic Memory , Hematopoietic Stem And Progenitor Cells , Il 6 , Cornell University , The Jackson Laboratory , Long Covid ,

Study suggests that epigenetic memory in innate immune cells could be the key to explaining long COVID

A new study may provide a partial explanation for the long-term immunologic phenomena associated with COVID-19. ....

Elizaveta Galitckaia Shutterstock , Epigenetic Memory , Innate Immune Cells , Image Credit , Their Progenitors , Called Peripheral Blood Mononuclear Cell , Progenitor Input Enrichment , Regulatory Chromatin , Coronavirus Disease Covid 19 , Bone Marrow , Covid 19 , Progenitor Cells , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Stem Cells ,