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Despite the considerable efficacy observed when targeting a dispensable lineage antigen, such as CD19 in B cell acute lymphoblastic leukaemia1,2, the broader applicability of adoptive immunotherapies is hampered by the absence of tumour-restricted antigens3–5. Acute myeloid leukaemia immunotherapies target genes expressed by haematopoietic stem/progenitor cells (HSPCs) or differentiated myeloid cells, resulting in intolerable on-target/off-tumour toxicity. Here we show that epitope engineering of donor HSPCs used for bone marrow transplantation endows haematopoietic lineages with selecti...

Critics say midget wrestling is an exploitative and dangerous spectacle that fuels public harassment and glorifies a derogatory slur. Promoters say, who cares?

Juneja, managing partner, India & EMEA (Europe, Middle East and Africa) at SoftBank Investment Advisers, most of the top technology companies in India are well capitalised and have cut costs over the past year, leading to their unwillingness to opt for a down round.

Kuala Lumpur: AmLife International Sdn. Bhd today staged its sleep health showcase themed “Sleep Your Way To A Younger and Healthier You!” to address increasing sleep issues and their connection to ageing and diseases at the One World Hotel.

More than 3,500 Participants Recorded at 2023 Digital Entertainment Leadership Forum (DELF)