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Verve Therapeutics Announces Interim Data for VERVE-101 Demonstrating First Human Proof-of-Concept for In Vivo Base Editing with Dose-Dependent Reductions in LDL-C and Blood PCSK9 Protein in Patients with Heterozygous Familial Hypercholesterolemia - Vimarsana News

Verve Therapeutics Announces Interim Data for VERVE-101 Demonstrating First Human Proof-of-Concept for In Vivo Base Editing with Dose-Dependent Reductions in LDL-C and Blood PCSK9 Protein in Patients with Heterozygous Familial Hypercholesterolemia

Published: November 12, 2023

LDL-C Reductions Up to 55% and Blood PCSK9 Protein Reductions Up to 84% Observed After a Single Infusion of VERVE-101 at Potentially Therapeutic Doses Safety Profile Supports Continued Development of...

Source: marketscreener.com
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United KingdomUnited StatesNew ZealandNew YorkJen RobinsonAndrew BellingerDeepakl BhattSekar KathiresanAshlea KosikowskiGlobenewswire IncIcahn School Of MedicineVerve Therapeutics IncSafety Profile Supports Continued DevelopmentCompany To Host Conference CallDrug AdministrationExchange CommissionObserved AfterSingle InfusionPotentially TherapeuticProfile Supports Continued DevelopmentInitiate Expansion CohortHost Conference CallWebcast TodaySinai Fuster Heart HospitalFuster Professor
89bio Publishes Positive Results from Phase 2 ENTRIGUE Trial of Pegozafermin in Patients with Severe Hypertriglyceridemia (SHTG) in Nature Medicine - Vimarsana News

89bio Publishes Positive Results from Phase 2 ENTRIGUE Trial of Pegozafermin in Patients with Severe Hypertriglyceridemia (SHTG) in Nature Medicine

Published: June 24, 2023

– Published data showed consistent and significant reductions in triglycerides, atherogenic lipoproteins and liver fat, and pegozafermin’s favorable safety and tolerability profile – – SHTG Phase 3 ENTRUST trial initiated in May 2...

Source: marketscreener.com
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United StatesSan FranciscoDeepakl BhattHank MansbachSheryl SeapyBryan MartinsIcahn School Of Medicine At Mount SinaiGlobenewswire IncLifesci AdvisorsMount SinaiNature MedicineChief Medical OfficerEngland JournalQuarterly ReportSafe HarborPrivate Securities Litigation Reform ActSci AdvisorsFuster ProfessorCardiovascular Medicine