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Where might future novel coronaviruses come from?

Where might future novel coronaviruses come from?
Researchers at the University of Liverpool, UK, have shown that the number of novel coronaviruses that could be generated in wild and domesticated animals is currently largely underestimated.
The team used a machine-learning pipeline to calculate the probability of different viruses combining in the same animal (recombination host) to produce new strains of coronaviruses.
The researchers predicted many more associations between coronaviruses and host species than have been observed to date. They also predicted 30 times more potential recombination hosts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19). ....

United Kingdom , Maya Wardeh , Sally Robertson , Nature Communications , University Of Liverpool , Image Credit , Asian Palm , Middle East , Corona Virus , Coronavirus Disease Covid 19 , Homologous Recombination , Sars Cov 2 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது கிஂக்டம் , சாலி ராபர்ட்சன் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் லிவர்பூல் , படம் கடன் , ஆசிய பனை , நடுத்தர கிழக்கு , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Study sheds light on pathological characteristics behind sudden cardiac death

Study sheds light on pathological characteristics behind sudden cardiac death
Nearly a half-million people a year die from sudden cardiac death (SCD) in the U.S. the result of malfunctions in the heart s electrical system.
A leading cause of SCD in young athletes is arrhythmogenic cardiomyopathy (ACM), a genetic disease in which healthy heart muscle is replaced over time by scar tissue (fibrosis) and fat.
Stephen Chelko, an assistant professor of biomedical sciences at the Florida State University College of Medicine, has developed a better understanding of the pathological characteristics behind the disease, as well as promising avenues for prevention. His findings are published in the current issue of ....

Stephen Chelko , Emily Henderson , Florida State University , National Research Council In Padova , College Of Medicine , Professor Of Biomedical Sciences , Florida State University College Of Medicine , Florida State University College , Science Translational , Assistant Professor , Biomedical Sciences , Florida State , National Research Council , Sudden Cardiac Death , Cell Death , எமிலி ஹென்டர்சன் , புளோரிடா நிலை பல்கலைக்கழகம் , தேசிய ஆராய்ச்சி சபை இல் ப்யாடோவ , கல்லூரி ஆஃப் மருந்து , ப்ரொஃபெஸர் ஆஃப் உயிர் மருத்துவ அறிவியல் , புளோரிடா நிலை பல்கலைக்கழகம் கல்லூரி ஆஃப் மருந்து , புளோரிடா நிலை பல்கலைக்கழகம் கல்லூரி , அறிவியல் மொழிபெயர்ப்பு , உதவியாளர் ப்ரொஃபெஸர் , உயிர் மருத்துவ அறிவியல் , புளோரிடா நிலை ,

Study reveals genetic signature of colibactin implicated in the development colorectal cancers

Study reveals genetic signature of colibactin implicated in the development colorectal cancers
Escherichia coli bacteria are constitutive members of the human gut microbiota. However, some strains produce a genotoxin called colibactin, which is implicated in the development of colorectal cancer.
While it has been shown that colibactin leaves very specific changes in the DNA of host cells that can be detected in colorectal cancer cells, such cancers take many years to develop, leaving the actual process by which a normal cell becomes cancerous obscure.
The group of Thomas F. Meyer at the Max Planck Institute for Infection Biology in Berlin together with their collaborators have now been able to catch colibactin in the act of inducing genetic changes that are characteristic of colorectal cancer cells and cause a transformed phenotype - after only a few hours of infection. ....

Thomasf Meyer , Amina Iftekhar , Michael Sigal , Emily Henderson , University Hospital , Max Planck Institute For Infection Biology , Max Planck Institute , Infection Biology , E Coli , Colorectal Cancer , Growth Factor , Stem Cells , அமினா இப்தெகர் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் மருத்துவமனை , தொற்று உயிரியல் , ஏ கோலி , பெருங்குடல் புற்றுநோய் , வளர்ச்சி காரணி , தண்டு செல்கள் ,

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer

Analyzing short strands of cell-free DNA in urine could help detect early-stage cancer
Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer. What if it were that easy, though, and cancer was detected in its very earliest stages when the disease responds more favorably to treatment and improved outcomes are more likely?
That was the question posed by scientists at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, who have found a way of zeroing in on early-stage cancer by analyzing short strands of cell-free DNA in urine. Their study s findings were published today in the scientific journal ....

United States , Muhammed Murtaza , Ajay Goel , Emily Henderson , Department Of Molecular Diagnostics , Tgen Center , Translational Genomics Research Institute Tgen , Baylor University , Translational Genomics Research Institute , Science Translational , Phoenix Children , Associate Professor , Noninvasive Diagnostics , Molecular Diagnostics , Experimental Therapeutics , Associate Director , Basic Science , Distinguished Professor , Pancreatic Cancer , ஒன்றுபட்டது மாநிலங்களில் , முஹம்மது முர்தஜ , அஜய கோயல் , எமிலி ஹென்டர்சன் , துறை ஆஃப் மூலக்கூறு பரிசோதனை , பேலர் பல்கலைக்கழகம் , மொழிபெயர்ப்பு மரபியல் ஆராய்ச்சி நிறுவனம் ,

Rocket Pharmaceuticals : Announces Participation at Upcoming Conferences

Rocket Pharmaceuticals, Inc. , a clinical-stage company advancing an integrated and sustainable pipeline of genetic therapies for rare childhood disorders announces participation at the following. | February 22, 2021 ....

Gaurav Shah , Healthcare Conference , Rocket Pharmaceuticals Inc , Rocket Pharmaceuticals , Global Healthcare , Chief Executive Officer , Annual Healthcare , Inc Stock Exchange , Press Release , The Rckt , கௌராவ் ஷா , சுகாதாரம் மாநாடு , ராக்கெட் மருந்துகள் இன்க் , ராக்கெட் மருந்துகள் , உலகளாவிய சுகாதாரம் , தலைமை நிர்வாகி அதிகாரி , ஆண்டு சுகாதாரம் , இன்க் ஸ்டாக் பரிமாற்றம் , ப்ரெஸ் வெளியீடு , குழந்தை பருவம் ,