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Probing Earth's mysterious inner core, and the most complete human genome to date | Science

Probing Earth's mysterious inner core, and the most complete human genome to date | Science
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Adam Phillippy , Paul Voosen , Sarah Crespi , It Consortium , National Human Genome Research Institute , Telomere To Consortium , Writer Paul Voosen , Genome Informatics Section ,

NSU researcher part of a flagship study on vertebrate genomes


Credit: Genome 10K Project
Study Take-Aways
Unprecedented novel discoveries have implications for characterizing biodiversity for all life, conservation, and human health and disease.
o This finding provides novel avenues of research to increase immune defenses, particularly relevant for emerging infectious diseases, such as the current COVID-19 pandemic.
The flagship paper presented whole genome sequence analyses of 16 vertebrate species to illustrate high quality, near error free, near complete, low cost reference genome assemblies.
o Though near 400 species have been sequenced at some level, the quality today reflects a quantum leap in precision sequence details and discovery.
FORT LAUDERDALE/DAVIE, Fla. - Two decades ago, the full genome sequence of humankind was released. It was funded by international government and philanthropic sources at a cost of billions of dollars. ....

United States , Fort Myers , New York , United Kingdom , Chevy Chase , San Diego , Puerto Rico , Fort Lauderdale , National Institutes Of Health , New Zealand , Department Of Education , District Of Columbia , Rockefeller University , San Diego Zoo , Sankt Peterburg , Palm Beach , Oxford Nanopore , Stephen Obrien , Richard Durbin , Pacific Biosciences , Erich Jarvis , Adam Phillippy , Kerstin Howe , Halmos College Of Arts , University Of Cambridge , Art Museum Fort Lauderdale ,

The Vertebrate Genomes Project introduces a new era of genome sequencing


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The Vertebrate Genomes Project (VGP) today announces their flagship study and associated publications focused on genome assembly quality and standardization for the field of genomics. This study includes 16 diploid high-quality, near error-free, and near complete vertebrate reference genome assemblies for species across all taxa with backbones (i.e., mammals, amphibians, birds, reptiles, and fishes) from five years of piloting the first phase of the VGP project.
Nature, with companion papers simultaneously published in other scientific journals, the VGP details numerous technological improvements based on these 16 genome assemblies. In the flagship study, the VGP demonstrates the feasibility of setting and achieving high-quality reference genome quality metrics using their state-of-the-art automated approach of combining long-read and long-range chromosome scaffolding approaches with novel algorithms that put the pieces of the genome assembly puzzle together. ....

New York , United States , National Institutes Of Health , New Zealand , Rockefeller University , United Kingdom , San Diego Zoo , Chevy Chase , San Diego , Oxford Nanopore , Adam Phillippy , Richard Durbin , Pacific Biosciences , Erich Jarvis , Kerstin Howe , K Community Of Scientists , San Diego Zoo Wildlife Alliance , University Of Cambridge , Vertebrate Genome Laboratory , Max Planck Society Of Germany , Albert Lasker Medical Research , Max Planck Institute Of Molecular Cell Biology , National Center , Uc Santa Cruz Genomics Institute Genome Browser , Wellcome Sanger Institute , Howard Hughes Medical Institute Investigator ,