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Study finds altered gut bacteria in people with early signs of Alzheimer's disease

People in the earliest stage of Alzheimer's disease -; after brain changes have begun but before cognitive symptoms become apparent -; harbor an assortment of bacteria in their intestines that differs from the gut bacteria of healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis. ....

Danielj Brennan , Gautam Dantas , Lily Ramsey , Conan Professor Of Laboratory , Washington University School Of Medicine , Washington University School , Science Translational Medicine , Conan Professor , Joanne Knight Alzheimer Disease Research Center , Lzheimer 39s Disease , Molecular Imaging ,

High-Dose Regimen Fixes Severe Obesity From Mutated Leptin

Children making certain dysfunctional variant forms of leptin as a result of genetic mutations required a hugely increased dose of a leptin analog to achieve weight loss and other clinical responses. ....

Ulm University Medical Center , New England Journal , Childhood Obesity , Weight Loss , Weight Management , Biologic Therapy , Genomic Medicine , Edicine Genomic , Ndocrine System ,