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Delirium and incident dementia in hospital patients in New South Wales, Australia: retrospective cohort study

Objectives To determine the strength and nature of the association between delirium and incident dementia in a population of older adult patients without dementia at baseline.

Design Retrospective cohort study using large scale hospital administrative data.

Setting Public and private hospitals in New South Wales, Australia between July 2001 and March 2020.

Participants Data were extracted for 650 590 hospital patients aged ≥65 years. Diagnoses of dementia and delirium were identified from ICD-10 (international classification of diseases, 10th revision) codes. Patients with dementia at baseline were excluded. Delirium-no delirium pairs were identified by matching personal and clinical characteristics, and were followed for more than five years.

Main outcome measures Cox proportional hazards models and Fine-Gray hazard models were used to estimate the associations of delirium with death and incident dementia, respectively. Delirium-outcome dose-response as ....

Shlomo Berkovsky , Ruthe Hubbard , Chao Xiong , Emilyh Gordon , Australian Frailty Network , Partnership Centre For Health Systems Sustainability , Partnership Centre For Health System Sustainability , Centre For Health Record Linkage , Health Records , Hospital Elder Life Program , Australasian Association Of Gerontology , National Health , Health Service Research Ethics Committee , Guidelines For Research , Research Council , New South Wales , Cognitive Impact , Health Record Linkage , Patient Data Collection , New South Wales Population , State Privacy Commissioner , Information Privacy Act , Medical Research Council , Partnership Centre , Health System , Health System Sustainability ,

Levels of pneumococcal conjugate vaccine coverage and indirect protection against invasive pneumococcal disease and pneumonia hospitalisations in Australia: An observational study

Levels of pneumococcal conjugate vaccine coverage and indirect protection against invasive pneumococcal disease and pneumonia hospitalisations in Australia: An observational study
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