Prenatal Folate May Program Hematopoietic Stem Cell Function Into Adulthood
The study findings have implications for the identification of novel pathways with which to selectively target folate-metabolism blood cancers.
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The study findings have implications for the identification of novel pathways with which to selectively target folate-metabolism blood cancers.
Jennifer R. Brown, MD, PhD, director of the Chronic Lymphocytic Leukemia (CLL) Center of the Division of Hematologic Malignancies at Dana-Farber Cancer Institute, discussed the updated findings from the phase 3 ALPINE trial of zanubrutinib vs ibrutinib in relapsed/refractory CLL (r/r CLL) at 39 months of follow-up.
Results confirm promising clinical activity, durable responses and favorable safety of lacutamab in heavily pretreated post-mogamulizumab Sézary Syndrome patients.Virtual KOL event will be held on Tuesday, December 12, 2023 at 7:00AM PST (4:00PM CET)MARSEILLE, France--(BUSINESS WIRE)--#immunotherapy--Innate Pharma S...
Zanubrutinib continued to demonstrate improved progression-free survival benefit over ibrutinib in the treatment of patients with relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma, according to extended follow-up data from the phase 3 ALPINE trial.
Obecabtagene autoleucel elicited durable responses in patients with relapsed or refractory B-cell acute lymphoblastic leukemia independent of leukemic burden at lymphodepletion, although better outcomes were observed in those with lower burden.